| Literature DB >> 207431 |
G G Nussdorfer, G Mazzocchi, G Neri, C Robba.
Abstract
Vinblastine treatment blocks corticosterone release from rat adrenal zona fasciculata without impairing hormone synthesis, and induces the formation of acid phosphatase-positive granular clumps at the juxta-sinusoidal pole of the cells. Autoradiography shows that ACTH administration to vinblastine-treated animals mobilizes the 3H-cholesterol stored in the lipid droplets and leads to a noticeable labelling of the granular clumps. The possible significance of these granules is discussed.Entities:
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Year: 1978 PMID: 207431 DOI: 10.1007/bf00209129
Source DB: PubMed Journal: Cell Tissue Res ISSN: 0302-766X Impact factor: 5.249