| Literature DB >> 20740532 |
Chen-I Wu1, Yi-Sheng Wang, Nelson G Chen, Chung-Yi Wu, Chung-Hsuan Chen.
Abstract
To date, mass spectrometric analysis of biomolecules has been primarily performed with either matrix-assisted laser desorption/ionization (MALDI) or electrospray ionization (ESI). In this work, ultrasound produced by a simple piezoelectric device is shown as an alternative method for soft ionization of biomolecules. Precursor ions of proteins, saccharides and fatty acids showed little fragmentation. Cavitation is considered as a primary mechanism for the ionization of biomolecules. Copyright 2010 John Wiley & Sons, Ltd.Entities:
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Year: 2010 PMID: 20740532 DOI: 10.1002/rcm.4677
Source DB: PubMed Journal: Rapid Commun Mass Spectrom ISSN: 0951-4198 Impact factor: 2.419