Literature DB >> 20740114

Conflicts of interest in research-towards a greater transparency.

Jeffrey P Braff.   

Abstract

Recently, substantial undisclosed financial Conflicts of Interest (COI) by researchers at academic medical centers have been discovered and reported in US Senate investigations, prompting large research institutions to take a close look at policies and procedures associated with the reporting and with the management of researcher COI. This article defines COI, reviews the background, describes the problems that arise, and offers solutions.

Entities:  

Year:  2010        PMID： 20740114      PMCID： PMC2912078          DOI： 10.7812/TPP/10-057

Source DB:  PubMed          Journal:  Perm J        ISSN： 1552-5767


  12 in total

1.  A national survey of policies on disclosure of conflicts of interest in biomedical research.

Authors:  S V McCrary; C B Anderson; J Jakovljevic; T Khan; L B McCullough; N P Wray; B A Brody
Journal:  N Engl J Med       Date:  2000-11-30       Impact factor: 91.245

2.  Conflict of interest and the public trust.

Authors:  C D DeAngelis
Journal:  JAMA       Date:  2000-11-01       Impact factor: 56.272

3.  Reporting financial conflicts of interest and relationships between investigators and research sponsors.

Authors:  C D DeAngelis; P B Fontanarosa; A Flanagin
Journal:  JAMA       Date:  2001-07-04       Impact factor: 56.272

4.  The effect of conflict of interest on biomedical research and clinical practice guidelines: can we trust the evidence in evidence-based medicine?

Authors:  John Abramson; Barbara Starfield
Journal:  J Am Board Fam Pract       Date:  2005 Sep-Oct

5.  Managing conflicts of interest in the conduct of clinical trials.

Authors:  Karine Morin; Herbert Rakatansky; Frank A Riddick; Leonard J Morse; John M O'Bannon; Michael S Goldrich; Priscilla Ray; Matthew Weiss; Robert M Sade; Monique A Spillman
Journal:  JAMA       Date:  2002-01-02       Impact factor: 56.272

6.  Money in biomedicine: The senator's sleuth.

Authors:  Meredith Wadman
Journal:  Nature       Date:  2009-09-17       Impact factor: 49.962

7.  Uniform format for disclosure of competing interests in ICMJE journals.

Authors:  Jeffrey M Drazen; Martin B Van der Weyden; Peush Sahni; Jacob Rosenberg; Ana Marusic; Christine Laine; Sheldon Kotzin; Richard Horton; Paul C Hébert; Charlotte Haug; Fiona Godlee; Frank A Frizelle; Peter W de Leeuw; Catherine D DeAngelis
Journal:  N Engl J Med       Date:  2009-10-13       Impact factor: 91.245

8.  Serving two masters--conflicts of interest in academic medicine.

Authors:  Bernard Lo
Journal:  N Engl J Med       Date:  2010-02-25       Impact factor: 91.245

Review 9.  Rofecoxib.

Authors:  J L Hillson; D E Furst
Journal:  Expert Opin Pharmacother       Date:  2000-07       Impact factor: 3.889

10.  Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control study.

Authors:  David J Graham; David Campen; Rita Hui; Michele Spence; Craig Cheetham; Gerald Levy; Stanford Shoor; Wayne A Ray
Journal:  Lancet       Date:  2005 Feb 5-11       Impact factor: 79.321
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