Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Structural evidence of glycoprotein assembly in cellular membrane compartments prior to Alphavirus budding.

Literature DB >> 20739526

Structural evidence of glycoprotein assembly in cellular membrane compartments prior to Alphavirus budding.

Pan Soonsawad¹, Li Xing, Emerson Milla, Juan M Espinoza, Masaaki Kawano, Michael Marko, Chyongere Hsieh, Hiromitsu Furukawa, Masahiro Kawasaki, Wattana Weerachatyanukul, Ranjana Srivastava, Susan W Barnett, Indresh K Srivastava, R Holland Cheng.

Abstract

Membrane glycoproteins of alphavirus play a critical role in the assembly and budding of progeny virions. However, knowledge regarding transport of viral glycoproteins to the plasma membrane is obscure. In this study, we investigated the role of cytopathic vacuole type II (CPV-II) through in situ electron tomography of alphavirus-infected cells. The results revealed that CPV-II contains viral glycoproteins arranged in helical tubular arrays resembling the basic organization of glycoprotein trimers on the envelope of the mature virions. The location of CPV-II adjacent to the site of viral budding suggests a model for the transport of structural components to the site of budding. Thus, the structural characteristics of CPV-II can be used in evaluating the design of a packaging cell line for replicon production.

Mesh：

Substances：

Year: 2010 PMID： 20739526 PMCID： PMC2953181 DOI： 10.1128/JVI.00036-10

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

36 in total

1. Locations of carbohydrate sites on alphavirus glycoproteins show that E1 forms an icosahedral scaffold.

Authors: Sergei V Pletnev; Wei Zhang; Suchetana Mukhopadhyay; Bonnie R Fisher; Raquel Hernandez; Dennis T Brown; Timothy S Baker; Michael G Rossmann; Richard J Kuhn
Journal: Cell Date: 2001-04-06 Impact factor: 41.582

Review 2. The emergence of electron tomography as an important tool for investigating cellular ultrastructure.

Authors: B F McEwen; M Marko
Journal: J Histochem Cytochem Date: 2001-05 Impact factor: 2.479

3. The missing link between envelope formation and fusion in alphaviruses.

Authors: H Garoff; R H Cheng
Journal: Trends Microbiol Date: 2001-09 Impact factor: 17.079

4. Membrane proteins organize a symmetrical virus.

Authors: K Forsell; L Xing; T Kozlovska; R H Cheng; H Garoff
Journal: EMBO J Date: 2000-10-02 Impact factor: 11.598

5. Electron tomography of frozen-hydrated isolated triad junctions.

Authors: T Wagenknecht; C-E Hsieh; B K Rath; S Fleischer; M Marko
Journal: Biophys J Date: 2002-11 Impact factor: 4.033

6. Semliki forest virus budding: assay, mechanisms, and cholesterol requirement.

Authors: Y E Lu; M Kielian
Journal: J Virol Date: 2000-09 Impact factor: 5.103

7. Acid-induced movements in the glycoprotein shell of an alphavirus turn the spikes into membrane fusion mode.

Authors: Lars Haag; Henrik Garoff; Li Xing; Lena Hammar; Sin-Tau Kan; R Holland Cheng
Journal: EMBO J Date: 2002-09-02 Impact factor: 11.598

8. Biogenesis of the Semliki Forest virus RNA replication complex.

Authors: P Kujala; A Ikäheimonen; N Ehsani; H Vihinen; P Auvinen; L Kääriäinen
Journal: J Virol Date: 2001-04 Impact factor: 5.103

9. Nucleic acid-dependent cross-linking of the nucleocapsid protein of Sindbis virus.

Authors: T L Tellinghuisen; R J Kuhn
Journal: J Virol Date: 2000-05 Impact factor: 5.103

10. Delivery and expression of heterologous genes in mammalian cells using self-replicating alphavirus vectors.

Authors: Gunilla B Karlsson; Peter Liljeström
Journal: Methods Mol Biol Date: 2004

33 in total

1. Molecular links between the E2 envelope glycoprotein and nucleocapsid core in Sindbis virus.

Authors: Jinghua Tang; Joyce Jose; Paul Chipman; Wei Zhang; Richard J Kuhn; Timothy S Baker
Journal: J Mol Biol Date: 2011-10-04 Impact factor: 5.469

2. Rescue of infectious particles from preassembled alphavirus nucleocapsid cores.

Authors: Jonathan E Snyder; Odisse Azizgolshani; Bingbing Wu; Yingpei He; Aih Cheun Lee; Joyce Jose; Daniel M Suter; Charles M Knobler; William M Gelbart; Richard J Kuhn
Journal: J Virol Date: 2011-04-06 Impact factor: 5.103

3. Probing the early temporal and spatial interaction of the Sindbis virus capsid and E2 proteins with reverse genetics.

Authors: Jonathan E Snyder; Christian J Berrios; Thomas J Edwards; Joyce Jose; Rushika Perera; Richard J Kuhn
Journal: J Virol Date: 2012-09-05 Impact factor: 5.103

Review 4. Revisiting an old friend: new findings in alphavirus structure and assembly.

Authors: Julie M Button; Shefah A Qazi; Joseph Che-Yen Wang; Suchetana Mukhopadhyay
Journal: Curr Opin Virol Date: 2020-07-16 Impact factor: 7.090

Review 5. Chikungunya virus: epidemiology, replication, disease mechanisms, and prospective intervention strategies.

Authors: Laurie A Silva; Terence S Dermody
Journal: J Clin Invest Date: 2017-03-01 Impact factor: 14.808

6. Neutralizing Monoclonal Antibodies Block Chikungunya Virus Entry and Release by Targeting an Epitope Critical to Viral Pathogenesis.

Authors: Jing Jin; Nathan M Liss; Dong-Hua Chen; Maofu Liao; Julie M Fox; Raeann M Shimak; Rachel H Fong; Daniel Chafets; Sonia Bakkour; Sheila Keating; Marina E Fomin; Marcus O Muench; Michael B Sherman; Benjamin J Doranz; Michael S Diamond; Graham Simmons
Journal: Cell Rep Date: 2015-12-10 Impact factor: 9.423

7. Neutralizing Antibodies Inhibit Chikungunya Virus Budding at the Plasma Membrane.

Authors: Jing Jin; Jesús G Galaz-Montoya; Michael B Sherman; Stella Y Sun; Cynthia S Goldsmith; Eileen T O'Toole; Larry Ackerman; Lars-Anders Carlson; Scott C Weaver; Wah Chiu; Graham Simmons
Journal: Cell Host Microbe Date: 2018-08-23 Impact factor: 21.023