Literature DB >> 20737496

Relation of mucous membrane alterations to oral intake during the first year after treatment for head and neck cancer.

Barbara Roa Pauloski1, Alfred W Rademaker, Jerilyn A Logemann, Donna Lundy, Michelle Bernstein, Carrie McBreen, Daphne Santa, Angela Campanelli, Lisa Kelchner, Bernice Klaben, Muveddet Discekici-Harris.   

Abstract

BACKGROUND: Acute oral mucositis is associated with pain and impaired swallowing. Little information is available on the effects of chronic mucositis on swallowing.
METHODS: Sixty patients treated for cancer of the head and neck were examined during the first year after their cancer treatment. Oral mucosa was rated with the Oral Mucositis Assessment Scale. Stimulated whole-mouth saliva, oral pain rating, percent of oral intake, and 2 subscales of the Performance Status Scale for Head and Neck (PSS-HN) cancer were also collected.
RESULTS: Mucositis scores and pain ratings decreased over time while functional measures of eating improved over time. Reduction in chronic mucositis was correlated with improved oral intake and diet.
CONCLUSION: Lack of association with pain was attributed to the absence of ulcerations. Continued impairment of oral intake during the first year posttreatment may be related to oral mucosal changes and other factors.
Copyright © 2010 Wiley Periodicals, Inc.

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Year:  2010        PMID: 20737496      PMCID: PMC4061735          DOI: 10.1002/hed.21542

Source DB:  PubMed          Journal:  Head Neck        ISSN: 1043-3074            Impact factor:   3.147


  42 in total

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Authors:  Jeri A Logemann; Barbara Roa Pauloski; Alfred W Rademaker; Cathy L Lazarus; Bharat Mittal; Joy Gaziano; Linda Stachowiak; Ellen MacCracken; Lisa A Newman
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6.  Exploring the Interplay Between Radiotherapy Dose and Physiological Changes in the Swallowing Mechanism in Patients Undergoing (Chemo)radiotherapy for Oropharynx Cancer.

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