Literature DB >> 20737024

THERAPEUTIC PERSPECTIVES ON THE COMBINATION OF ALPHA-LIPOIC ACID AND VITAMIN E.

Oscar Gonzalez-Perez1, Rocio E Gonzalez-Castaneda.   

Abstract

Alpha-lipoic acid and vitamin E have synergistic effects, as determined in models of oxidant radical lesions. This review summarizes recent findings showing that the combination of alpha-lipoic acid plus vitamin E has beneficial effects in reducing oxidative damage in ischemic or other oxidation-related pathological events. Both antioxidants are common in the normal human diet and side effects are very rare. Therefore, alpha-lipoic acid and vitamin E can counteract oxidative processes and could have an important role in clinical medicine.

Entities:  

Year:  2006        PMID： 20737024      PMCID： PMC2925278          DOI： 10.1016/j.nutres.2005.11.011

Source DB:  PubMed          Journal:  Nutr Res        ISSN： 0271-5317            Impact factor:   3.315


  51 in total

1.  The effect of dietary selenium and vitamin E on glutathione peroxidase and glutathione in the rat.

Authors:  D L Scott; J Kelleher; M S Losowsky
Journal:  Biochem Soc Trans       Date:  1976       Impact factor: 5.407

2.  The effect of dietary alpha-tocopherol on the experimental vasogenic brain edema.

Authors:  M Stoffel; S Berger; F Staub; J Eriskat; K Jacob; A Baethmann
Journal:  J Neurotrauma       Date:  1997-05       Impact factor: 5.269

Review 3.  Vitamin E kinetics and the function of tocopherol regulatory proteins.

Authors:  D H Blatt; S W Leonard; M G Traber
Journal:  Nutrition       Date:  2001-10       Impact factor: 4.008

4.  Effects of triple antioxidant combination (vitamin E, vitamin C and alpha-lipoic acid) with insulin on lipid and cholesterol levels and fatty acid composition of brain tissue in experimental diabetic and non-diabetic rats.

Authors:  Yusuf Ozkan; Okkeş Yilmaz; Ali Ihsan Oztürk; Yasemin Erşan
Journal:  Cell Biol Int       Date:  2005-09       Impact factor: 3.612

5.  Protective effects of vitamin E on carbon tetrachloride-induced liver damage in rats.

Authors:  M Naziroğlu; M Cay; B Ustündağ; M Aksakal; H Yekeler
Journal:  Cell Biochem Funct       Date:  1999-12       Impact factor: 3.685

6.  The influence of vitamin E and dihydrolipoic acid on cardiac energy and glutathione status under hypoxia-reoxygenation.

Authors:  N Haramaki; H Assadnazari; G Zimmer; V Schepkin; L Packer
Journal:  Biochem Mol Biol Int       Date:  1995-10

7.  Effects of alpha-tocopherol on lipid peroxidation and mitochondrial reduction of tetraphenyl tetrazolium in the rat brain.

Authors:  M A Villalobos; J P De La Cruz; T Carrasco; J M Smith-Agreda; F Sánchez de la Cuesta
Journal:  Brain Res Bull       Date:  1994       Impact factor: 4.077

8.  Alpha-lipoic acid prevents buthionine sulfoximine-induced cataract formation in newborn rats.

Authors:  I Maitra; E Serbinova; H Trischler; L Packer
Journal:  Free Radic Biol Med       Date:  1995-04       Impact factor: 7.376

9.  Antioxidant activity of dihydrolipoate against microsomal lipid peroxidation and its dependence on alpha-tocopherol.

Authors:  H Scholich; M E Murphy; H Sies
Journal:  Biochim Biophys Acta       Date:  1989-02-20

10.  Protection by glutathione and other thiol compounds against the loss of protein thiols and tocopherol homologs during microsomal lipid peroxidation.

Authors:  M E Murphy; H Scholich; H Sies
Journal:  Eur J Biochem       Date:  1992-11-15
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  4 in total

1.  Enhancement of lipid stability of broiler breast meat and meat products fed on alpha lipoic acid and alpha tocopherol acetate supplemented feed.

Authors:  Muhammad Sohaib; Faqir Muhammad Anjum; Muhammad Issa Khan; Muhammad Sajid Arshad; Muhammad Shahid
Journal:  Lipids Health Dis       Date:  2012-05-28       Impact factor: 3.876

2.  Effect of vitamin E and alpha lipoic acid on intestinal development associated with wooden breast myopathy in broilers.

Authors:  Ji Wang; Daniel L Clark; Sheila K Jacobi; Sandra G Velleman
Journal:  Poult Sci       Date:  2020-12-23       Impact factor: 4.014

3.  Supplementation of Dietary Quercetin and Vitamin E Promotes the Intestinal Structure and Immune Barrier Integrity in Aged Breeder Hens.

Authors:  Felix Kwame Amevor; Zhifu Cui; Xiaxia Du; Zifan Ning; Xun Deng; Dan Xu; Gang Shu; Youhao Wu; Xueqing Cao; Wei Shuo; Yaofu Tian; Diyan Li; Yan Wang; Yao Zhang; Xiaohui Du; Qing Zhu; Xue Han; Xiaoling Zhao
Journal:  Front Immunol       Date:  2022-03-21       Impact factor: 7.561

4.  Glial plasticity after hexahydrobenzene exposure.

Authors:  Tania Campos-Ordonez; Oscar Gonzalez-Perez
Journal:  Neural Regen Res       Date:  2016-03       Impact factor: 5.135
  4 in total

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