Literature DB >> 2073688

Microencapsulation using emulsification/solvent evaporation: an overview of techniques and applications.

P J Watts1, M C Davies, C D Melia.   

Abstract

This review describes the microencapsulation of pharmaceuticals using the technique of emulsification-solvent evaporation. Guidelines are given for development of encapsulation processes for drugs with either high or low aqueous solubilities. Methods for microsphere characterization and assessment are detailed. The properties of a range of encapsulating polymers are described with examples of drugs encapsulated. The article concludes by speculating the clinical potential of microsphere-based drug delivery systems.

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Year:  1990        PMID： 2073688

Source DB:  PubMed          Journal:  Crit Rev Ther Drug Carrier Syst        ISSN： 0743-4863            Impact factor:   4.889


  15 in total

1.  Bone tissue engineering in a rotating bioreactor using a microcarrier matrix system.

Authors:  E A Botchwey; S R Pollack; E M Levine; C T Laurencin
Journal:  J Biomed Mater Res       Date:  2001-05

2.  Fourier transform-Raman spectroscopy for the qualitative and quantitative characterization of sulfasalazine-containing polymeric microspheres.

Authors:  P J Watts; A Tudor; S J Church; P J Hendra; P Turner; C D Melia; M C Davies
Journal:  Pharm Res       Date:  1991-10       Impact factor: 4.200

3.  A novel method of preparing PLGA microcapsules utilizing methylethyl ketone.

Authors:  H Sah; M S Smith; R T Chern
Journal:  Pharm Res       Date:  1996-03       Impact factor: 4.200

4.  Preparation and characterization of gelatin surface modified PLGA microspheres.

Authors:  M J Tsung; D J Burgess
Journal:  AAPS PharmSci       Date:  2001

5.  Sciatic nerve blockade with lipid-protein-sugar particles containing bupivacaine.

Authors:  D S Kohane; M Lipp; R C Kinney; N Lotan; R Langer
Journal:  Pharm Res       Date:  2000-10       Impact factor: 4.200

6.  Nerve growth factor expression by PLG-mediated lipofection.

Authors:  Kevin J Whittlesey; Lonnie D Shea
Journal:  Biomaterials       Date:  2005-11-28       Impact factor: 12.479

7.  Preparation of monodisperse biodegradable polymer microparticles using a microfluidic flow-focusing device for controlled drug delivery.

Authors:  Qiaobing Xu; Michinao Hashimoto; Tram T Dang; Todd Hoare; Daniel S Kohane; George M Whitesides; Robert Langer; Daniel G Anderson
Journal:  Small       Date:  2009-07       Impact factor: 13.281

8.  Nano and Microparticulate Chitosan Based System for Formulation of Carvedilol Rapid Melt Tablet.

Authors:  Ravindra Patil; Vishal Pande; Raju Sonawane
Journal:  Adv Pharm Bull       Date:  2015-06-01

9.  Silk coatings on PLGA and alginate microspheres for protein delivery.

Authors:  Xiaoqin Wang; Esther Wenk; Xiao Hu; Guillermo R Castro; Lorenz Meinel; Xianyan Wang; Chunmei Li; Hans Merkle; David L Kaplan
Journal:  Biomaterials       Date:  2007-06-20       Impact factor: 12.479

10.  Differential Impact of Plasma Proteins on the Adhesion Efficiency of Vascular-Targeted Carriers (VTCs) in Blood of Common Laboratory Animals.

Authors:  Katawut Namdee; Daniel J Sobczynski; Peter J Onyskiw; Omolola Eniola-Adefeso
Journal:  Bioconjug Chem       Date:  2015-11-09       Impact factor: 4.774
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