Literature DB >> 20735795

Enamel matrix derivative proteins for the treatment of proximal class II furcation involvements: a prospective 24-month randomized clinical trial.

Renato Corrêa Viana Casarin1, Erica Del Peloso Ribeiro, Francisco Humberto Nociti, Antônio Wilson Sallum, Gláucia Maria Bovi Ambrosano, Enilson Antônio Sallum, Márcio Zaffalon Casati.   

Abstract

OBJECTIVE: This study aimed to evaluate the response of proximal furcations treated with enamel matrix derivative proteins (EMD) in a 24-month follow-up.
MATERIALS AND METHODS: Twelve patients presenting bilateral class II proximal furcation with vertical probing depth (PD) ≥5 mm and bleeding on probing were selected. The furcations were assigned to: a control group (n=12), open flap debridement (OFD)+EDTA and a test group (n=12) - OFD+EDTA+EMD. The gingival margin position, PD, relative vertical and horizontal clinical attachment level (RVCAL and RHCAL), vertical and horizontal bone level (VBL and HBL) and furcation closure were evaluated before treatment and after 6, 12 and 24 months.
RESULTS: After follow-up, no statistical difference could be seen between groups. At 24 months, the test group showed 1.9 ± 1.6 mm PD reduction whereas the control group showed 1.0 ± 1.3 mm PD reduction. RHCAL gains of the control and the test group were 0.7 ± 1.3 and 1.4 ± 0.9 mm, respectively. However, at 24 months, the test group only presented five remaining class II furcations versus 10 furcations in the control group (p<0.05).
CONCLUSION: It could be concluded that EMD therapy promoted a reduction in the number of proximal furcations presenting a diagnosis of class II after 24 months of treatment compared with OFD therapy.
© 2010 John Wiley & Sons A/S.

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Year:  2010        PMID: 20735795     DOI: 10.1111/j.1600-051X.2010.01614.x

Source DB:  PubMed          Journal:  J Clin Periodontol        ISSN: 0303-6979            Impact factor:   8.728


  7 in total

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2.  Enamel matrix protein derivative and/or synthetic bone substitute for the treatment of mandibular class II buccal furcation defects. A 12-month randomized clinical trial.

Authors:  Lucas Araujo Queiroz; Mauro Pedrine Santamaria; Marcio Z Casati; Karina Silverio Ruiz; Francisco Nociti; Antonio Wilson Sallum; Enilson A Sallum
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Authors:  Meng-Yao Chiu; Cho-Ying Lin; Pe-Yi Kuo
Journal:  BMC Oral Health       Date:  2022-05-06       Impact factor: 3.747

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Authors:  Vandana J Rathva
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  7 in total

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