Farzin Forooghian1, Nishi Gulati, Douglas A Jabs. 1. Department of Ophthalmology, Mount Sinai School of Medicine, New York, New York 10029, USA. farzin.forooghian@gmail.com
Abstract
PURPOSE: To describe restoration of retinal architecture following systemic immunosuppressive treatment in a patient with birdshot chorioretinopathy (BSCR). DESIGN: Case report. METHODS: A patient with BSCR and vitritis, reduced electroretinographic responses, and a constricted visual field was treated with prednisone and mycophenolate mofetil. RESULTS: Spectral domain optical coherence tomography (SD-OCT) at baseline demonstrated a disruption of retinal architecture. After 4 months of treatment retinal architecture, as visualized on SD-OCT, was restored to normal. CONCLUSIONS: Treatment of BSCR with systemic immunosuppression can result in restoration of disrupted retinal architecture. This structural improvement can be visualized and assessed using SD-OCT.
PURPOSE: To describe restoration of retinal architecture following systemic immunosuppressive treatment in a patient with birdshot chorioretinopathy (BSCR). DESIGN: Case report. METHODS: A patient with BSCR and vitritis, reduced electroretinographic responses, and a constricted visual field was treated with prednisone and mycophenolate mofetil. RESULTS: Spectral domain optical coherence tomography (SD-OCT) at baseline demonstrated a disruption of retinal architecture. After 4 months of treatment retinal architecture, as visualized on SD-OCT, was restored to normal. CONCLUSIONS: Treatment of BSCR with systemic immunosuppression can result in restoration of disrupted retinal architecture. This structural improvement can be visualized and assessed using SD-OCT.
Authors: Colin J Chu; Philipp Herrmann; Livia S Carvalho; Sidath E Liyanage; James W B Bainbridge; Robin R Ali; Andrew D Dick; Ulrich F O Luhmann Journal: PLoS One Date: 2013-05-14 Impact factor: 3.240