Literature DB >> 20735077

1,1-Dibromo-1-alkenes as valuable partners in the copper-catalyzed direct alkynylation of azoles.

Beatriz Pacheco Berciano1, Sabrina Lebrequier, François Besselièvre, Sandrine Piguel.   

Abstract

The copper-catalyzed direct alkynylation of azoles with 1,1-dibromo-1-alkenes as electrophiles is described. These easily accessible substrates are a useful addition to the field of direct alkynylations in an efficient and functional group tolerant reaction to provide a straightforward entry to diverse alkynyl heterocycles.

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Year:  2010        PMID: 20735077     DOI: 10.1021/ol1016433

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  4 in total

1.  Synthesis of 1,3-Diynes via Cadiot-Chodkiewicz Coupling of Volatile, in Situ Generated Bromoalkynes.

Authors:  Phil C Knutson; Haleigh E Fredericks; Eric M Ferreira
Journal:  Org Lett       Date:  2018-10-17       Impact factor: 6.005

2.  Oxidant speciation and anionic ligand effects in the gold-catalyzed oxidative coupling of arenes and alkynes.

Authors:  Manuel Hofer; Teresa de Haro; Enrique Gómez-Bengoa; Alexandre Genoux; Cristina Nevado
Journal:  Chem Sci       Date:  2019-07-31       Impact factor: 9.825

3.  Nickel(ii)-catalyzed tandem C(sp2)-H bond activation and annulation of arenes with gem-dibromoalkenes.

Authors:  Yun Shi; Meng-Sheng Li; Fangdong Zhang; Baohua Chen
Journal:  RSC Adv       Date:  2018-08-13       Impact factor: 3.361

4.  Copper-catalyzed CuAAC/intramolecular C-H arylation sequence: Synthesis of annulated 1,2,3-triazoles.

Authors:  Rajkumar Jeyachandran; Harish Kumar Potukuchi; Lutz Ackermann
Journal:  Beilstein J Org Chem       Date:  2012-10-16       Impact factor: 2.883

  4 in total

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