Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Antigen processing and presentation in vivo: the microenvironment as a crucial factor.

Literature DB >> 2073316

Antigen processing and presentation in vivo: the microenvironment as a crucial factor.

Abstract

Antigen processing and presentation in vitro is an increasingly well understood phenomenon. However, in vivo, a large number of variables conspire to obscure and confuse. In this article, Nico van Rooijen attempts to bring order to events that occur in the spleen after antigenic challenge: starting with the large body of reliable in vitro data he incorporates information on splenic anatomy, cell trafficking and the cellular microenvironment to arrive at a physiological model for antigen handling in vivo.

Mesh：

Substances：
Antigens

Year: 1990 PMID： 2073316 DOI： 10.1016/0167-5699(90)90171-5

Source DB: PubMed Journal: Immunol Today ISSN： 0167-5699

Keyword Cloud
Cited

10 in total

1. A synthetic peptide to the E glycoprotein of Murray Valley encephalitis virus defines multiple virus-reactive T- and B-cell epitopes.

Authors: J H Mathews; J T Roehrig; J R Brubaker; A R Hunt; J E Allan
Journal: J Virol Date: 1992-11 Impact factor: 5.103

2. Histological and functional differentiation of non-lymphoid cells in the chicken spleen.

Authors: S H Jeurissen; E Claassen; E M Janse
Journal: Immunology Date: 1992-09 Impact factor: 7.397

3. Complement component 3 interactions with coxsackievirus B3 capsid proteins: innate immunity and the rapid formation of splenic antiviral germinal centers.

Authors: D R Anderson; C M Carthy; J E Wilson; D Yang; D V Devine; B M McManus
Journal: J Virol Date: 1997-11 Impact factor: 5.103

10. Evaluation of Alum-Naltrexone Adjuvant Activity, on Efficacy of Anti-Leishmania Immunization with Autoclaved Leishmania major (MRHO/IR/75/ER) Antigens in BALB/C Mice.

Authors: Habib Mohammadzadeh Hajipirloo; Arezoo Bozorgomd; Shahram Shahabi; Khosrow Hazrati Tappeh; Seyed Ahmad Karamati
Journal: Iran J Parasitol Date: 2014-09 Impact factor: 1.012

10 in total

Antigen processing and presentation in vivo: the microenvironment as a crucial factor.

1. A synthetic peptide to the E glycoprotein of Murray Valley encephalitis virus defines multiple virus-reactive T- and B-cell epitopes.

2. Histological and functional differentiation of non-lymphoid cells in the chicken spleen.

3. Complement component 3 interactions with coxsackievirus B3 capsid proteins: innate immunity and the rapid formation of splenic antiviral germinal centers.

4. Lymph node trafficking and antigen presentation by endobronchial eosinophils.

Review 5. Liposomes as delivery systems in the prevention and treatment of infectious diseases.

6. Characterisation of Peptide5 systemic administration for treating traumatic spinal cord injured rats.

7. The demonstration of an essential role for macrophages in the in vivo generation of IgG2a antibodies.

8. Immune-complex trapping in the splenic ellipsoids of rainbow trout (Oncorhynchus mykiss).

9. The role of various compartments in the chicken spleen during an antigen-specific humoral response.

10. Evaluation of Alum-Naltrexone Adjuvant Activity, on Efficacy of Anti-Leishmania Immunization with Autoclaved Leishmania major (MRHO/IR/75/ER) Antigens in BALB/C Mice.