Literature DB >> 20732810

Design, synthesis, and anticancer activities of novel perfluoroalkyltriazole-appended 2'-deoxyuridines.

Sun Min Park1, Heeju Yang, Song-Kyu Park, Hwan Mook Kim, Byeang Hyean Kim.   

Abstract

We have focused on the C5-modification of 2'-deoxyuridine with substituted heterocycles for bioactivity, such as antiviral or anticancer activity. Herein, we report a novel class of nucleoside analogues with perfluoroalkyltriazole moiety as an anticancer drug candidate.
Copyright © 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 20732810     DOI： 10.1016/j.bmcl.2010.07.126

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  8 in total

1.  Design, synthesis, antiviral and cytotoxic evaluation of novel acyclic phosphonate nucleotide analogues with a 5,6-dihydro-1H-[1,2,3]triazolo[4,5-d]pyridazine-4,7-dione system.

Authors:  Emilia Bankowska; Jan Balzarini; Iwona E Głowacka; Andrzej E Wróblewski
Journal:  Monatsh Chem       Date:  2014-01-25       Impact factor: 1.451

2.  Design, synthesis, antiviral and cytostatic evaluation of novel isoxazolidine nucleotide analogues with a 1,2,3-triazole linker.

Authors:  Dorota G Piotrowska; Jan Balzarini; Iwona E Głowacka
Journal:  Eur J Med Chem       Date:  2011-11-20       Impact factor: 6.514

Review 3.  Fluorinated triazoles as privileged potential candidates in drug development-focusing on their biological and pharmaceutical properties.

Authors:  Ihsan Ullah; Muhammad Ilyas; Muhammad Omer; Muhammad Alamzeb; Muhammad Sohail
Journal:  Front Chem       Date:  2022-08-09       Impact factor: 5.545

4.  Synthesis and Antiviral Evaluation of Nucleoside Analogues Bearing One Pyrimidine Moiety and Two D-Ribofuranosyl Residues.

Authors:  Olga V Andreeva; Bulat F Garifullin; Vladimir V Zarubaev; Alexander V Slita; Iana L Yesaulkova; Alexandrina S Volobueva; Mayya G Belenok; Maria A Man'kova; Liliya F Saifina; Marina M Shulaeva; Alexandra D Voloshina; Anna P Lyubina; Vyacheslav E Semenov; Vladimir E Kataev
Journal:  Molecules       Date:  2021-06-16       Impact factor: 4.411

5.  Synthesis of 1,2,3-triazolyl nucleoside analogues and their antiviral activity.

Authors:  Olga V Andreeva; Bulat F Garifullin; Vladimir V Zarubaev; Alexander V Slita; Iana L Yesaulkova; Liliya F Saifina; Marina M Shulaeva; Maya G Belenok; Vyacheslav E Semenov; Vladimir E Kataev
Journal:  Mol Divers       Date:  2020-09-15       Impact factor: 2.943

Review 6.  Chemical architecture and applications of nucleic acid derivatives containing 1,2,3-triazole functionalities synthesized via click chemistry.

Authors:  Tim Efthymiou; Wei Gong; Jean-Paul Desaulniers
Journal:  Molecules       Date:  2012-10-26       Impact factor: 4.411

7.  The synthesis, antiviral, cytostatic and cytotoxic evaluation of a new series of acyclonucleotide analogues with a 1,2,3-triazole linker.

Authors:  Iwona E Głowacka; Jan Balzarini; Andrzej E Wróblewski
Journal:  Eur J Med Chem       Date:  2013-10-30       Impact factor: 6.514

8.  Design, synthesis, antiviral and cytostatic evaluation of novel isoxazolidine nucleotide analogues with a carbamoyl linker.

Authors:  Kamil Kokosza; Jan Balzarini; Dorota G Piotrowska
Journal:  Bioorg Med Chem       Date:  2013-01-16       Impact factor: 3.641
  8 in total

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