Literature DB >> 2073117

Effects of butenafine hydrochloride, a new benzylamine derivative, on experimental tinea pedis in guinea pigs.

T Arika1, M Yokoo, T Maeda, K Amemiya, H Yamaguchi.   

Abstract

Butenafine is a new antifungal benzylamine. The efficacy of butenafine was investigated in an experimental tinea pedis model in guinea pigs, which is pathologically similar to natural infections in humans. Butenafine (0.1 ml) in 0.2 to 1.0% solutions was applied to the site of infection. Treatment was started on day 10 postinfection and was continued for 20 days. Butenafine applied once daily exhibited excellent dose-related therapeutic efficacy. The efficacy of butenafine was significantly superior to those tolnaftate, clotrimazole, and bifonazole.

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Year:  1990        PMID： 2073117      PMCID： PMC172032          DOI： 10.1128/AAC.34.11.2254

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  3 in total

1.  Effects of butenafine hydrochloride, a new benzylamine derivative, on experimental dermatophytosis in guinea pigs.

Authors:  T Arika; M Yokoo; T Hase; T Maeda; K Amemiya; H Yamaguchi
Journal:  Antimicrob Agents Chemother       Date:  1990-11       Impact factor: 5.191

2.  In vivo antimycotic activity of naftifine.

Authors:  G Petranyi; A Georgopoulos; H Mieth
Journal:  Antimicrob Agents Chemother       Date:  1981-03       Impact factor: 5.191

3.  Experimental tinea pedis induced by non-abrasive inoculation of Trichophyton mentagrophytes arthrospores on the plantar part of a guinea pig foot.

Authors:  S Fujita; T Matsuyama
Journal:  J Med Vet Mycol       Date:  1987-08
  3 in total
  9 in total

1.  In vitro and in vivo antidermatophyte activities of NND-502, a novel optically active imidazole antimycotic agent.

Authors:  Y Niwano; N Kuzuhara; H Kodama; M Yoshida; T Miyazaki; H Yamaguchi
Journal:  Antimicrob Agents Chemother       Date:  1998-04       Impact factor: 5.191

Review 2.  Relevant Animal Models in Dermatophyte Research.

Authors:  Ludivine Cambier; Marie-Pierre Heinen; Bernard Mignon
Journal:  Mycopathologia       Date:  2016-10-11       Impact factor: 2.574

3.  In vitro antifungal activity of KP-103, a novel triazole derivative, and its therapeutic efficacy against experimental plantar tinea pedis and cutaneous candidiasis in guinea pigs.

Authors:  Y Tatsumi; M Yokoo; T Arika; H Yamaguchi
Journal:  Antimicrob Agents Chemother       Date:  2001-05       Impact factor: 5.191

Review 4.  Butenafine.

Authors:  W McNeely; C M Spencer
Journal:  Drugs       Date:  1998-03       Impact factor: 9.546

5.  Two mechanisms of butenafine action in Candida albicans.

Authors:  W Iwatani; T Arika; H Yamaguchi
Journal:  Antimicrob Agents Chemother       Date:  1993-04       Impact factor: 5.191

6.  Anti-Trichophyton mentagrophytes activity and percutaneous permeation of butenafine in guinea pigs.

Authors:  T Arika; T Hase; M Yokoo
Journal:  Antimicrob Agents Chemother       Date:  1993-02       Impact factor: 5.191

7.  Topical treatment with butenafine significantly lowers relapse rate in an interdigital tinea pedis model in guinea pigs.

Authors:  T Arika; M Yokoo; H Yamaguchi
Journal:  Antimicrob Agents Chemother       Date:  1992-11       Impact factor: 5.191

8.  Short-term topical therapy of experimental tinea pedis in guinea pigs with lanoconazole, a new imidazole antimycotic agent.

Authors:  Y Niwano; T Tabuchi; K Kanai; H Hamaguchi; K Uchida; H Yamaguchi
Journal:  Antimicrob Agents Chemother       Date:  1995-10       Impact factor: 5.191

Review 9.  Animal model of dermatophytosis.

Authors:  Tsuyoshi Shimamura; Nobuo Kubota; Kazutoshi Shibuya
Journal:  J Biomed Biotechnol       Date:  2012-04-29
  9 in total

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