Literature DB >> 20730412

[Therapy-resistant otitis externa with additional tympanic membrane perforation: local therapy using N-chlorotaurine and dexamethasone].

M Lumassegger1, M Nagl, C Pototschnig, A Neher.   

Abstract

Ear canal infections may not always be clinically distinguished between a bacterial otitis externa, an otomycosis or a mixed infection. In addition, tympanic membrane perforations are often not immediately apparent. The use of a broad-spectrum antiseptic agent without an inner ear toxic effect would therefore be beneficial. We report the case of a female patient suffering from intractable otitis externa with tympanic membrane perforation, who was successfully treated locally with a mixture of 1% NCT and 0.1% dexamethasone.

Entities:  

Mesh:

Substances:

Year:  2010        PMID: 20730412     DOI: 10.1007/s00106-010-2082-1

Source DB:  PubMed          Journal:  HNO        ISSN: 0017-6192            Impact factor:   1.284


  17 in total

1.  Activity of N-chlorotaurine against herpes simplex- and adenoviruses.

Authors:  M Nagl; C Larcher; W Gottardi
Journal:  Antiviral Res       Date:  1998-04       Impact factor: 5.970

2.  Tolerability of N-chlorotaurine in chronic rhinosinusitis applied via yamik catheter.

Authors:  Andreas Neher; Hannes Fischer; Elisabeth Appenroth; Cornelia Lass-Flörl; Astrid Mayr; Andreas Gschwendtner; Hanno Ulmer; Thaddaeus F Gotwald; Michaela Gstöttner; Vladimir Kozlov; Markus Nagl
Journal:  Auris Nasus Larynx       Date:  2005-07-22       Impact factor: 1.863

3.  Killing of schistosomula by taurine chloramine and taurine bromamine.

Authors:  M Yazdanbakhsh; C M Eckmann; D Roos
Journal:  Am J Trop Med Hyg       Date:  1987-07       Impact factor: 2.345

4.  Tolerability and efficacy of N-chlorotaurine in comparison with chloramine T for the treatment of chronic leg ulcers with a purulent coating: a randomized phase II study.

Authors:  M Nagl; V A Nguyen; W Gottardi; H Ulmer; R Höpfl
Journal:  Br J Dermatol       Date:  2003-09       Impact factor: 9.302

5.  Chlorination of endogenous amines by isolated neutrophils. Ammonia-dependent bactericidal, cytotoxic, and cytolytic activities of the chloramines.

Authors:  M B Grisham; M M Jefferson; D F Melton; E L Thomas
Journal:  J Biol Chem       Date:  1984-08-25       Impact factor: 5.157

6.  Chemical properties of N-chlorotaurine sodium, a key compound in the human defence system.

Authors:  Waldemar Gottardi; Markus Nagl
Journal:  Arch Pharm (Weinheim)       Date:  2002-11       Impact factor: 3.751

7.  Cytotoxic activity of N-chlorotaurine on Acanthamoeba spp.

Authors:  Ursula Fürnkranz; Markus Nagl; Waldemar Gottardi; Martina Köhsler; Horst Aspöck; Julia Walochnik
Journal:  Antimicrob Agents Chemother       Date:  2007-11-26       Impact factor: 5.191

8.  Short communication: rapid preparation of preventive and therapeutic whole-killed retroviral vaccines using the microbicide taurine chloramine.

Authors:  A K Dudani; A Martyres; H Fliss
Journal:  AIDS Res Hum Retroviruses       Date:  2008-04       Impact factor: 2.205

9.  Antibacterial activity of mometasone furoate.

Authors:  Andreas Neher; Michaela Gstöttner; Arne Scholtz; Markus Nagl
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2008-05

10.  Antimicrobial activity of dexamethasone and its combination with N-chlorotaurine.

Authors:  Andreas Neher; Roland Arnitz; Michaela Gstöttner; Dirk Schäfer; Eva-Maria Kröss; Markus Nagl
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2008-06
View more
  5 in total

1.  [Diagnosis and treatment of external otitis].

Authors:  Florian Simon
Journal:  HNO       Date:  2020-11       Impact factor: 1.284

Review 2.  Current Opinion on the Therapeutic Capacity of Taurine-Containing Halogen Derivatives in Infectious and Inflammatory Diseases.

Authors:  Janusz Marcinkiewicz; Markus Nagl; Anthony Kyriakopoulos; Maria Walczewska; Magdalena Skóra; Paulina Skalska
Journal:  Adv Exp Med Biol       Date:  2022       Impact factor: 3.650

3.  N-Chlorotaurine Exhibits Fungicidal Activity against Therapy-Refractory Scedosporium Species and Lomentospora prolificans.

Authors:  Michaela Lackner; Ulrike Binder; Martin Reindl; Beyhan Gönül; Hannes Fankhauser; Christian Mair; Markus Nagl
Journal:  Antimicrob Agents Chemother       Date:  2015-08-03       Impact factor: 5.191

4.  Otomycosis with Perforated Tympanic Membrane: Self medication with Topical Antifungal Solution versus Medicated Ear Wick.

Authors:  A S Abou-Halawa; M A Khan; A A Alrobaee; A A Alzolibani; H A Alshobaili
Journal:  Int J Health Sci (Qassim)       Date:  2012-01

Review 5.  N-Chlorotaurine, a Promising Future Candidate for Topical Therapy of Fungal Infections.

Authors:  Markus Nagl; Roland Arnitz; Michaela Lackner
Journal:  Mycopathologia       Date:  2017-07-12       Impact factor: 2.574

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.