Arthur Kummer1, Francisco Cardoso, Antonio Lucio Teixeira. 1. Neuropsychiatric Branch, Neurology Unit, University Hospital, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil. r2kummer@hotmail.com
Abstract
UNLABELLED: Anxiety is common in Parkinson's disease (PD), but studies concerning specific anxiety disorders are scarce. Essential psychometric properties of anxiety rating scales are also lacking. OBJECTIVE: To investigate general anxiety disorder (GAD) in PD and psychometric properties of the Hamilton Anxiety Rating Scale (Ham-A). METHOD: Ninety-one PD patients underwent neurological and psychiatric examination, which included the MINI-Plus, the Ham-A and the Hamilton Depression Rating Scale (Ham-D). RESULTS: GAD was present in 30.8% of PD patients. Patients with GAD had longer disease duration (p=0.044) and were in use of higher doses of levodopa (p=0.034). They also tended to have more motor fluctuations and dyskinesias. The group with GAD scored higher in Ham-A (p<0.001), in the somatic (p=0.004) and psychic (p<0.001) subscales of Ham-A, and in Ham-D (p=0.004). The Ham-A showed good internal consistency (Cronbach's alpha=0.893) and a cutoff score of 10/11 is suggested to screen for GAD. CONCLUSION: GAD is frequent in PD and the Ham-A may be a useful instrument to screen for this disorder.
UNLABELLED: Anxiety is common in Parkinson's disease (PD), but studies concerning specific anxiety disorders are scarce. Essential psychometric properties of anxiety rating scales are also lacking. OBJECTIVE: To investigate general anxiety disorder (GAD) in PD and psychometric properties of the Hamilton Anxiety Rating Scale (Ham-A). METHOD: Ninety-one PDpatients underwent neurological and psychiatric examination, which included the MINI-Plus, the Ham-A and the Hamilton Depression Rating Scale (Ham-D). RESULTS: GAD was present in 30.8% of PDpatients. Patients with GAD had longer disease duration (p=0.044) and were in use of higher doses of levodopa (p=0.034). They also tended to have more motor fluctuations and dyskinesias. The group with GAD scored higher in Ham-A (p<0.001), in the somatic (p=0.004) and psychic (p<0.001) subscales of Ham-A, and in Ham-D (p=0.004). The Ham-A showed good internal consistency (Cronbach's alpha=0.893) and a cutoff score of 10/11 is suggested to screen for GAD. CONCLUSION: GAD is frequent in PD and the Ham-A may be a useful instrument to screen for this disorder.
Authors: Matthew Swan; Nancy Doan; Robert A Ortega; Matthew Barrett; William Nichols; Laurie Ozelius; Jeannie Soto-Valencia; Sarah Boschung; Andres Deik; Harini Sarva; Jose Cabassa; Brooke Johannes; Deborah Raymond; Karen Marder; Nir Giladi; Joan Miravite; William Severt; Rivka Sachdev; Vicki Shanker; Susan Bressman; Rachel Saunders-Pullman Journal: J Neurol Sci Date: 2016-08-30 Impact factor: 3.181
Authors: Nadeeka N W Dissanayaka; Elizabeth White; John D O'Sullivan; Rodney Marsh; Peter A Silburn; David A Copland; George D Mellick; Gerard J Byrne Journal: Mov Disord Clin Pract Date: 2015-04-06
Authors: Sarah E Giron; Martin F Bjurstrom; Charles A Griffis; F Michael Ferrante; Irene I Wu; Andrea L Nicol; Tristan R Grogan; Joseph F Burkard; Michael R Irwin; Elizabeth Crabb Breen Journal: Pain Med Date: 2018-05-01 Impact factor: 3.637
Authors: Gustavo C Medeiros; Daniela G Sampaio; Eric W Leppink; Samuel R Chamberlain; Jon E Grant Journal: J Behav Addict Date: 2016-06 Impact factor: 6.756