Literature DB >> 20728851

Fat embolism syndrome in long bone fracture--clinical experience in a tertiary referral center in Taiwan.

I-Tzun Tsai1, Chin-Jung Hsu, Ying-Hao Chen, Yi-Chin Fong, Horng-Chaung Hsu, Chun-Hao Tsai.   

Abstract

BACKGROUND: Fat embolism syndrome (FES) is a potentially fatal complication of long bone fractures. There have been no reports of FES in long bone fractures in this decade in Taiwan. The purpose of this study was to review the FES experiences in a tertiary referral center between January 1997 and February 2008.
METHODS: Between January 1997 and February 2008, 13 patients with long bone fractures with documented FES in our institution were reviewed. FES was diagnosed clinically by at least 2 major criteria or 1 major with at least 4 minor signs of Gurd's criteria.
RESULTS: The incidences of FES, less than those reported in the literature, were 0.15% in fracture of the tibia, 0.78% in fracture of the femur and 2.4% in multiple fractures. The mortality rate of FES, similar to other available results, was about 7.7%. All cases were less than 35 years old, except for 1 70-year-old male. Fat embolism occurred within an average of 48.5 hours after long bone fracture. Eleven presented with sudden drop in hemoglobin level, dropping 4.2 g/dL on average. Nine presented with thrombocytopenia, and 10 presented with sudden drop in platelet count, dropping 140,000/dL on average. Two had cerebral sequelae without recovery at the last 48-month follow-up.
CONCLUSION: This 12-year interval retrospective study revealed modern epidemiologic results for FES in long bone fracture. Compared with the available literature in the recent decade, the incidence of FES in long bone fracture in our institution is less and the mortality rate is similar. Copyright 2010 Elsevier. Published by Elsevier B.V. All rights reserved.

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Year:  2010        PMID: 20728851     DOI: 10.1016/S1726-4901(10)70088-5

Source DB:  PubMed          Journal:  J Chin Med Assoc        ISSN: 1726-4901            Impact factor:   2.743


  10 in total

1.  Fat embolism syndrome in blunt trauma patients with extremity fractures.

Authors:  Miriam Alpert; Areg Grigorian; John Scolaro; James Learned; Matthew Dolich; Catherine M Kuza; Michael Lekawa; Jeffry Nahmias
Journal:  J Orthop       Date:  2020-09-06

2.  [Post-traumatic fat embolism syndrome].

Authors:  Adnane Mohamed Berdai; Abdelkarim Shimi; Mohammed Khatouf
Journal:  Pan Afr Med J       Date:  2014-02-02

3.  Bone marrow necrosis and fat embolism syndrome: a dreadful complication of hemoglobin sickle cell disease.

Authors:  Eduardo Pelegrineti Targueta; André Carramenha de Góes Hirano; Fernando Peixoto Ferraz de Campos; João Augusto Dos Santos Martines; Silvana Maria Lovisolo; Aloisio Felipe-Silva
Journal:  Autops Case Rep       Date:  2017-12-08

4.  Isolated and early-onset cerebral fat embolism syndrome in a multiply injured patient: a rare case.

Authors:  Chin-Kai Huang; Chih-Yuan Huang; Chia-Lung Li; Jui-Ming Yang; Chin-Hsien Wu; Chih-Hui Chen; Po-Ting Wu
Journal:  BMC Musculoskelet Disord       Date:  2019-08-17       Impact factor: 2.362

5.  Cerebral fat embolism in the absence of a long bone fracture: A rare case report.

Authors:  James B Fowler; Brian Fiani; Kasra Sarhadi; Vladimir Cortez
Journal:  Surg Neurol Int       Date:  2021-03-02

6.  A Rare Case of Fat Embolism Syndrome Masquerading as COVID-19 Pneumonia.

Authors:  Zaheer Faizi; Daniel W Kim; Ammar Humayun; Amber Batool; Ashanthi Ratnasekera
Journal:  Cureus       Date:  2022-03-22

7.  Fat Embolism Syndrome and in-Hospital Mortality Rates According to Patient Age: A Large Nationwide Retrospective Study.

Authors:  Sung Huang Laurent Tsai; Chien-Hao Chen; Eric H Tischler; Shyam J Kurian; Tung-Yi Lin; Chun-Yi Su; Greg Michael Osgood; Amber Mehmood; Tsai-Sheng Fu
Journal:  Clin Epidemiol       Date:  2022-08-19       Impact factor: 5.814

8.  Cerebral fat embolism syndrome after long bone fracture due to gunshot injury.

Authors:  Latif Duran; Servet Kayhan; Celal Kati; Hizir Ufuk Akdemir; Kemal Balci; Yucel Yavuz
Journal:  Indian J Crit Care Med       Date:  2014-03

9.  Fat Embolism Syndrome in Fracture Tibia Treated By Unreamed Interlocking Nail.

Authors:  Chandra Prakash Pal; Harish Kumar; Karuna Shankar Dinkar; Alok Agrawal
Journal:  J Orthop Case Rep       Date:  2013 Jan-Mar

10.  Cerebral Fat Embolism: Neuroprotective Goals in an Unusual Cause of Altered Mental Status.

Authors:  Keerthana K Kumar; Premkumar Nattanamai
Journal:  Cureus       Date:  2018-07-26
  10 in total

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