| Literature DB >> 20728440 |
Jarmila Kliescikova1, Jaroslav Kulda, Eva Nohynkova.
Abstract
Propylene glycol used as an ophthalmic demulcent in certain contact-lens care systems has been included recently among factors responsible for increasing Acanthamoeba keratitis. In this study, we provide evidence that propylene glycol as well as examined contact-lens solutions containing it induce rapid differentiation of acanthamoebae into pseudocysts. The partial resistance of the pseudocysts and their reversibility to viable trophozoites even after 24-h exposure to the contact-lens solutions indicate a potential risk of infection to contact-lens users.Entities:
Mesh:
Substances:
Year: 2010 PMID: 20728440 DOI: 10.1016/j.exppara.2010.08.014
Source DB: PubMed Journal: Exp Parasitol ISSN: 0014-4894 Impact factor: 2.011