Literature DB >> 20726684

Impact of ankylosing spondylitis on work in patients across the UK.

E L Healey1, K L Haywood, K P Jordan, A Garratt, J C Packham.   

Abstract

OBJECTIVES: To examine the impact of ankylosing spondylitis (AS) on patients across the UK and to identify factors associated with unemployment, absenteeism, and presenteeism.
METHODS: One thousand patients with AS from 10 specialist rheumatology centres across the UK were invited to participate in a study evaluating a new outcome measure. Patients completed a questionnaire, which included questions relating to their work, sociodemographic and clinical characteristics.
RESULTS: The questionnaire was completed by 612 patients (438 males; 72%). The mean age of the participants was 50.8 (SD 12.2) years, mean disease duration was 17.3 (SD 11.7) years, and mean symptom duration 22.4 (SD 12.4) years. A total of 206 (40%) patients of working age were not employed. Factors associated with not being employed were social deprivation [odds ratio (OR) 3.52, 95% confidence interval (CI) 2.14-5.80], poor function (OR 3.42, 95% CI 1.90-6.13), depression (OR 2.05, 95% CI 1.12-3.78), increasing age (OR 1.05 per year, 95% CI 1.02-1.08), and longer disease duration (OR 1.03 per year, 95% CI 1.01-1.06). Disease activity (OR 3.24, 95% CI 1.11-9.48) and depression (OR 3.22, 95% CI 1.22-8.48) were associated with absenteeism, while depression (OR 5.69, 95% CI 1.77-18.27, disease activity (OR 3.97, 95% CI 1.76-8.98), anxiety (OR 3.90, 95% CI 1.83-8.31), self-efficacy (OR 0.71, 95% CI 0.58-0.86), and increasing age (OR 1.04 per year, 95% CI 1.00-1.08) were associated with presenteeism.
CONCLUSION: Psychological, sociodemographic, and disease-related factors were all found to be related to work status. These factors should be taken into account when considering early treatment and management. Depression, in particular, appears to be associated with employment, absenteeism, and presenteeism, and should therefore be prioritized in clinical practice.

Entities:  

Mesh:

Year:  2010        PMID: 20726684     DOI: 10.3109/03009742.2010.487838

Source DB:  PubMed          Journal:  Scand J Rheumatol        ISSN: 0300-9742            Impact factor:   3.641


  24 in total

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2.  Greek adaptation and validation of the Ankylosing Spondylitis Quality of Life (ASQoL) measure.

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3.  Sociodemographic and disease-related factors are associated with patient-reported anxiety and depression in spondyloarthritis patients in the Swedish SpAScania cohort.

Authors:  Jorit J L Meesters; Ingemar F Petersson; Stefan Bergman; Emma Haglund; Lennart T H Jacobsson; Ann Bremander
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4.  Patients with well-established ankylosing spondylitis show limited deterioration in a ten-year prospective cohort study.

Authors:  E L Healey; K L Haywood; K P Jordan; A M Garratt; J C Packham
Journal:  Clin Rheumatol       Date:  2012-09-27       Impact factor: 2.980

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Review 6.  T cell Repertoire Profiling and the Mechanism by which HLA-B27 Causes Ankylosing Spondylitis.

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7.  Predictors of presenteeism and activity impairment outside work in patients with spondyloarthritis.

Authors:  Emma Haglund; Ingemar F Petersson; Ann Bremander; Stefan Bergman
Journal:  J Occup Rehabil       Date:  2015-06

8.  Adaptation and validation of the Ankylosing Spondylitis Work Instability Scale (AS-WIS) for use in Turkey.

Authors:  Ayşe A Küçükdeveci; Şebnem Ataman; Aysun Genç; Şehim Kutlay; Atilla H Elhan; Derya Őztuna; Alan Tennant
Journal:  Rheumatol Int       Date:  2014-06-03       Impact factor: 2.631

9.  The role of smoking in the development and progression of structural damage in axial SpA patients: A systematic review and meta-analysis.

Authors:  Servet Akar; Yusuf Cem Kaplan; Sertaç Ecemiş; Elif Keskin-Arslan; Önay Gercik; Sercan Gücenmez; Dilek Solmaz
Journal:  Eur J Rheumatol       Date:  2018-10-01

10.  The Cost of Ankylosing Spondylitis in the UK Using Linked Routine and Patient-Reported Survey Data.

Authors:  Roxanne Cooksey; Muhammad J Husain; Sinead Brophy; Helen Davies; Muhammad A Rahman; Mark D Atkinson; Ceri J Phillips; Stefan Siebert
Journal:  PLoS One       Date:  2015-07-17       Impact factor: 3.240

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