Literature DB >> 207265

Complete loss of heparin-releasable triacylglycerol lipase activity after collagenase treatment of the rat liver.

J Thomas, L J Debeer, G P Mannaerts.   

Abstract

Lipolytic activity at pH 8.5-9.5 was lowered by approx. 80% in homogenates from livers perfused with collagenase or heparin. No heparin-releasable lipase activity was detected in hepatocytes isolated by collagenase treatment. It is concluded that crude collagenase completely inactivates the plasma-membrane-bound heparin-releasable lipase.

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Year:  1978        PMID： 207265      PMCID： PMC1185676          DOI： 10.1042/bj1720177

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  13 in total

1.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

2.  Metabolic effects of hypoglycemic sulfonylureas. 3. Effect of chlorpropamide on energy metabolism and ketogenesis in the isolated perfused rat liver.

Authors:  G Mannaerts; L Debeer; P J De Schepper
Journal:  Biochem Pharmacol       Date:  1974-01-01       Impact factor: 5.858

3.  Characterization, subcellular localization, and partial purification of a heparin-released triglyceride lipase from rat liver.

Authors:  G Assmann; R M Krauss; D S Fredrickson; R I Levy
Journal:  J Biol Chem       Date:  1973-03-25       Impact factor: 5.157

4.  Identification of an adipose tissue-like lipoprotein lipase in perfusates of chicken liver.

Authors:  A Bensadoun; T L Koh
Journal:  J Lipid Res       Date:  1977-11       Impact factor: 5.922

5.  Effect of sulfonylureas on triglyceride metabolism in the rat liver: possible role of the lysosomes in hepatic lipolysis.

Authors:  L J Debeer; J Thomas; G Mannaerts; P J DeSchepper
Journal:  J Clin Invest       Date:  1977-02       Impact factor: 14.808

6.  Selective measurement of two different triglyceride lipase activities in rat postheparin plasma.

Authors:  R M Krauss; H G Windmueller; R I Levy; D S Fredrickson
Journal:  J Lipid Res       Date:  1973-05       Impact factor: 5.922

7.  Effects of anti-microtubular agents and cycloheximide on the metabolism of chylomicron cholesteryl esters by hepatocyte suspensions.

Authors:  A Nilsson
Journal:  Biochem J       Date:  1977-02-15       Impact factor: 3.857

8.  Uptake and degradation of cholesterol ester-labelled rat plasma lipoproteins in purified rat hepatocytes and nonparenchymal liver cells.

Authors:  C A Drevon; T Berg; K R Norum
Journal:  Biochim Biophys Acta       Date:  1977-04-26

9.  Rat high density lipoprotein subfraction (HDL3) uptake and catabolism by isolated rat liver parenchymal cells.

Authors:  T Nakai; P S Otto; D L Kennedy; T F Whayne
Journal:  J Biol Chem       Date:  1976-08-25       Impact factor: 5.157

10.  Gluconeogenesis in the perfused rat liver.

Authors:  R Hems; B D Ross; M N Berry; H A Krebs
Journal:  Biochem J       Date:  1966-11       Impact factor: 3.857
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  3 in total

1.  The effects of fasting and streptozotocin diabetes on the triglyceride lipase activity of rat liver plasma membranes.

Authors:  T Nomura; A Iguchi; H Matsunaga; N Sakamoto
Journal:  Lipids       Date:  1982-08       Impact factor: 1.880

2.  Role of glycerol 3-phosphate and glycerophosphate acyltransferase in the nutritional control of hepatic triacylglycerol synthesis.

Authors:  P E Declercq; L J Debeer; G P Mannaerts
Journal:  Biochem J       Date:  1982-04-15       Impact factor: 3.857

Review 3.  Short-term regulation of hepatic triacylglycerol metabolism by insulin and glucagon.

Authors:  A C Beynen; M J Geelen
Journal:  Vet Res Commun       Date:  1982-05       Impact factor: 2.459
  3 in total

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