BACKGROUND: The self-approximating translumenal access technique (STAT) has been shown to provide a safe and reliable means of abdominal access for natural orifice translumenal endoscopic surgery (NOTES). However, the feasibility of using STAT for translumenal organ resection is unknown. This study aimed to evaluate the technical performance of organ resection using STAT, the integrity of the STAT gastric tunnel after organ resection, and the postoperative morbidity of organ resection using STAT. METHODS: In this study, 14 domestic swine underwent transgastric organ resection (7 cholecystectomies, 7 uterine horn resections) followed by sequential removal of two different sizes of standardized specimens. Evaluation of operative injury to the tunnel and difficulty of specimen extraction was performed. After 2 weeks of observation, necropsy was performed for evaluation and documentation of gross findings. RESULTS: The mean operating room time (intubation recovery) was 4.1 h. A tunnel with a mean length of 12 cm and a mean width of 4 cm was created. The tunnel remained fully intact in 14 of 14 animals after organ resection, in 13 of 13 animals after balloon extraction, and in 12 of 14 animals after rigid specimen extraction (1 clinically significant tear occurred). Postoperatively, all the animals gained weight appropriately. Necropsy findings included adhesions (n = 4), bile leak (n = 2), minor lap-port abscess (n = 1), and ventral hernia (n = 1). CONCLUSIONS: Although this study was a limited, prospective, animal survival study without a control arm, it again indicates that STAT allows safe abdominal access, a reliable means of closure, and directed endoscope positioning. Although one significant mucosal tear did occur, this study suggests STAT will tolerate the mechanical forces of peroral transgastric procedures provided the organ resected is small to moderate in size (<8 × 3 cm).
BACKGROUND: The self-approximating translumenal access technique (STAT) has been shown to provide a safe and reliable means of abdominal access for natural orifice translumenal endoscopic surgery (NOTES). However, the feasibility of using STAT for translumenal organ resection is unknown. This study aimed to evaluate the technical performance of organ resection using STAT, the integrity of the STAT gastric tunnel after organ resection, and the postoperative morbidity of organ resection using STAT. METHODS: In this study, 14 domestic swine underwent transgastric organ resection (7 cholecystectomies, 7 uterine horn resections) followed by sequential removal of two different sizes of standardized specimens. Evaluation of operative injury to the tunnel and difficulty of specimen extraction was performed. After 2 weeks of observation, necropsy was performed for evaluation and documentation of gross findings. RESULTS: The mean operating room time (intubation recovery) was 4.1 h. A tunnel with a mean length of 12 cm and a mean width of 4 cm was created. The tunnel remained fully intact in 14 of 14 animals after organ resection, in 13 of 13 animals after balloon extraction, and in 12 of 14 animals after rigid specimen extraction (1 clinically significant tear occurred). Postoperatively, all the animals gained weight appropriately. Necropsy findings included adhesions (n = 4), bile leak (n = 2), minor lap-port abscess (n = 1), and ventral hernia (n = 1). CONCLUSIONS: Although this study was a limited, prospective, animal survival study without a control arm, it again indicates that STAT allows safe abdominal access, a reliable means of closure, and directed endoscope positioning. Although one significant mucosal tear did occur, this study suggests STAT will tolerate the mechanical forces of peroral transgastric procedures provided the organ resected is small to moderate in size (<8 × 3 cm).
Authors: Kazuki Sumiyama; Christopher J Gostout; Elizabeth Rajan; Timothy A Bakken; Mary A Knipschield; Sydney Chung; Peter B Cotton; Robert H Hawes; Anthony N Kalloo; Sergey V Kantsevoy; Pankaj J Pasricha Journal: Gastrointest Endosc Date: 2007-06 Impact factor: 9.427
Authors: S P Shih; S V Kantsevoy; A N Kalloo; P Magno; S A Giday; C-W Ko; N V Isakovich; O Meireles; E J Hanly; M R Marohn Journal: Surg Endosc Date: 2007-06-26 Impact factor: 4.584
Authors: Michael F McGee; Jeffrey M Marks; Raymond P Onders; Amitabh Chak; Michael J Rosen; Christina P Williams; Judy Jin; Steve J Schomisch; Jeffrey L Ponsky Journal: Gastrointest Endosc Date: 2008-04-14 Impact factor: 9.427
Authors: Eric Mark Pauli; Randy S Haluck; Adrian M Ionescu; Ann M Rogers; Timothy R Shope; Matthew T Moyer; Arnab Biswas; Abraham Mathew Journal: Surg Endosc Date: 2009-12-24 Impact factor: 4.584
Authors: Stefan von Delius; Sonja Gillen; Emmanouil Doundoulakis; Armin Schneider; Dirk Wilhelm; Adam Fiolka; Stefan Wagenpfeil; Roland M Schmid; Hubertus Feussner; Alexander Meining Journal: Gastrointest Endosc Date: 2008-06-17 Impact factor: 9.427
Authors: M Ryou; R D Pai; R Pai; J S Sauer; J Sauer; D W Rattner; D Rattner; C C Thompson; C Thompson Journal: Surg Endosc Date: 2006-12-08 Impact factor: 3.453
Authors: Abraham Mathew; Jonathan M Tomasko; Eric M Pauli; Matthew T Moyer; Jegan Gopal; Brooke B Ancrile; Ann M Rogers; Randy S Haluck Journal: Surg Endosc Date: 2011-04-13 Impact factor: 4.584