| Literature DB >> 2072459 |
L A Oberg1, J Wirkkula, D Mourich, J C Leong.
Abstract
The ribonucleoprotein gene of infectious hematopoietic necrosis virus (IHNV) has been expressed in Escherichia coli as a trpE fusion protein. This viral protein does not induce protective immunity to lethal IHNV infection in fish, and virus-neutralizing antibodies do not react with this viral protein. However, when it was administered with a bacterial lysate containing a region of the IHNV glycoprotein, there was enhanced resistance in immunized fish to lethal virus infection.Entities:
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Year: 1991 PMID: 2072459 PMCID: PMC248890 DOI: 10.1128/JVI.65.8.4486-4489.1991
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103