Literature DB >> 2072447

Generation and analysis of nonhomologous RNA-RNA recombinants in brome mosaic virus: sequence complementarities at crossover sites.

J J Bujarski1, A M Dzianott.   

Abstract

All three single-stranded RNAs of the brome mosaic virus (BMV) genome contain a highly conserved, 193-base 3' noncoding region. To study the recombination between individual BMV RNA components, barley plants were infected with a mixture of in vitro-transcribed wild-type BMV RNAs 1 and 2 and an RNA3 mutant that carried a deletion near the 3' end. This generated a population of both homologous and nonhomologous 3' recombinant BMV RNA3 variants. Sequencing revealed that these recombinants were derived by either single or double crossovers with BMV RNA1 or RNA2. The primary sequences at recombinant junctions did not show any similarity. However, they could be aligned to form double-stranded heteroduplexes. This suggested that local hybridizations among BMV RNAs may support intermolecular exchanges.

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Year:  1991        PMID： 2072447      PMCID： PMC248849          DOI： 10.1128/JVI.65.8.4153-4159.1991

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  30 in total

1.  Similarity in structure and function of the 3'-terminal region of the four brome mosaic viral RNAs.

Authors:  M Bastin; R Dasgupta; T C Hall; P Kaesberg
Journal:  J Mol Biol       Date:  1976-06-05       Impact factor: 5.469

2.  Isolation and biochemical characterization of intertypic recombinants of foot-and-mouth disease virus.

Authors:  D McCahon; A M King; D S Roe; W R Slade; J W Newman; A M Cleary
Journal:  Virus Res       Date:  1985-07       Impact factor: 3.303

3.  Use of Chenopodium hybridum facilitates isolation of brome mosaic virus RNA recombinants.

Authors:  A L Rao; B P Sullivan; T C Hall
Journal:  J Gen Virol       Date:  1990-06       Impact factor: 3.891

4.  A defective interfering RNA that contains a mosaic of a plant virus genome.

Authors:  B I Hillman; J C Carrington; T J Morris
Journal:  Cell       Date:  1987-11-06       Impact factor: 41.582

5.  A tobacco mosaic virus-hybrid expresses and loses an added gene.

Authors:  W O Dawson; D J Lewandowski; M E Hilf; P Bubrick; A J Raffo; J J Shaw; G L Grantham; P R Desjardins
Journal:  Virology       Date:  1989-09       Impact factor: 3.616

6.  Three-dimensional models of the tRNA-like 3' termini of some plant viral RNAs.

Authors:  K Rietveld; C W Pleij; L Bosch
Journal:  EMBO J       Date:  1983       Impact factor: 11.598

7.  Recombination between satellite RNAs of turnip crinkle virus.

Authors:  P J Cascone; C D Carpenter; X H Li; A E Simon
Journal:  EMBO J       Date:  1990-06       Impact factor: 11.598

8.  Multiple recombination sites at the 5'-end of murine coronavirus RNA.

Authors:  J G Keck; S A Stohlman; L H Soe; S Makino; M M Lai
Journal:  Virology       Date:  1987-02       Impact factor: 3.616

9.  A clustering of RNA recombination sites adjacent to a hypervariable region of the peplomer gene of murine coronavirus.

Authors:  L R Banner; J G Keck; M M Lai
Journal:  Virology       Date:  1990-04       Impact factor: 3.616

10.  Modulation of replication, aminoacylation and adenylation in vitro and infectivity in vivo of BMV RNAs containing deletions within the multifunctional 3' end.

Authors:  J J Bujarski; P Ahlquist; T C Hall; T W Dreher; P Kaesberg
Journal:  EMBO J       Date:  1986-08       Impact factor: 11.598
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  29 in total

1.  Genetic recombination in brome mosaic virus: effect of sequence and replication of RNA on accumulation of recombinants.

Authors:  P D Nagy; J J Bujarski
Journal:  J Virol       Date:  1992-11       Impact factor: 5.103

2.  Reversion of Q beta RNA phage mutants by homologous RNA recombination.

Authors:  K Palasingam; P N Shaklee
Journal:  J Virol       Date:  1992-04       Impact factor: 5.103

3.  RNA structural elements determine frequency and sites of nonhomologous recombination in an animal plus-strand RNA virus.

Authors:  Sophia Austermann-Busch; Paul Becher
Journal:  J Virol       Date:  2012-04-24       Impact factor: 5.103

4.  Homologous crossovers among molecules of brome mosaic bromovirus RNA1 or RNA2 segments in vivo.

Authors:  Anna Urbanowicz; Magdalena Alejska; Piotr Formanowicz; Jacek Blazewicz; Marek Figlerowicz; Jozef J Bujarski
Journal:  J Virol       Date:  2005-05       Impact factor: 5.103

Review 5.  RNA recombination in animal and plant viruses.

Authors:  M M Lai
Journal:  Microbiol Rev       Date:  1992-03

6.  Efficient in vitro system of homologous recombination in brome mosaic bromovirus.

Authors:  Rafal Wierzchoslawski; Jozef J Bujarski
Journal:  J Virol       Date:  2006-06       Impact factor: 5.103

7.  RNA synthesis by the brome mosaic virus RNA-dependent RNA polymerase in human cells reveals requirements for de novo initiation and protein-protein interaction.

Authors:  Chennareddy V Subba-Reddy; Brady Tragesser; Zhili Xu; Barry Stein; C T Ranjith-Kumar; C Cheng Kao
Journal:  J Virol       Date:  2012-02-08       Impact factor: 5.103

8.  Engineering of homologous recombination hotspots with AU-rich sequences in brome mosaic virus.

Authors:  P D Nagy; J J Bujarski
Journal:  J Virol       Date:  1997-05       Impact factor: 5.103

9.  A mutation in the putative RNA polymerase gene inhibits nonhomologous, but not homologous, genetic recombination in an RNA virus.

Authors:  M Figlerowicz; P D Nagy; J J Bujarski
Journal:  Proc Natl Acad Sci U S A       Date:  1997-03-04       Impact factor: 11.205

10.  Recombination between defective tombusvirus RNAs generates functional hybrid genomes.

Authors:  K A White; T J Morris
Journal:  Proc Natl Acad Sci U S A       Date:  1994-04-26       Impact factor: 11.205
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