Literature DB >> 20723817

Advances in the prediction and natural history of type 1 diabetes.

Ezio Bonifacio1, Anette G Ziegler.   

Abstract

Type 1 diabetes (T1D) has the hallmark characteristics of autoimmunity superimposed on genetic susceptibility. Both genes (HLA) and immune markers (autoantibodies) have been validated as predictive markers of the subsequent development of the disease in higher-risk relatives and the lower-risk general population. Over the last three decades, using a combination of genes, immune, and metabolic markers, clinicians are now able to quantify an individual's disease risk from 1 in 100,000 to more than 1 in 2. This article reviews these biomarkers and T1D prediction strategies, and discusses potential implications of prediction and natural history for the pathogenesis of T1D. Copyright 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID： 20723817     DOI： 10.1016/j.ecl.2010.05.007

Source DB:  PubMed          Journal:  Endocrinol Metab Clin North Am        ISSN： 0889-8529            Impact factor:   4.741


  20 in total

Review 1.  Novel biomarkers in type 1 diabetes.

Authors:  Yulan Jin; Jin-Xiong She
Journal:  Rev Diabet Stud       Date:  2012-12-28

2.  Anti-Insulin B Cells Are Poised for Antigen Presentation in Type 1 Diabetes.

Authors:  Jamie L Felton; Damian Maseda; Rachel H Bonami; Chrys Hulbert; James W Thomas
Journal:  J Immunol       Date:  2018-06-27       Impact factor: 5.422

3.  Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression.

Authors:  Tania Habib; S Alice Long; Peter L Samuels; Archana Brahmandam; Megan Tatum; Andrew Funk; Anne M Hocking; Karen Cerosaletti; Michael T Mason; Elizabeth Whalen; David J Rawlings; Carla Greenbaum; Jane H Buckner
Journal:  Diabetes       Date:  2019-03-20       Impact factor: 9.461

Review 4.  The pathogenesis and natural history of type 1 diabetes.

Authors:  Mark A Atkinson
Journal:  Cold Spring Harb Perspect Med       Date:  2012-11-01       Impact factor: 6.915

Review 5.  Genetics of the HLA region in the prediction of type 1 diabetes.

Authors:  Janelle A Noble; Ana M Valdes
Journal:  Curr Diab Rep       Date:  2011-12       Impact factor: 4.810

6.  Genetic and Small Molecule Disruption of the AID/RAD51 Axis Similarly Protects Nonobese Diabetic Mice from Type 1 Diabetes through Expansion of Regulatory B Lymphocytes.

Authors:  Jeremy J Ratiu; Jeremy J Racine; Muneer G Hasham; Qiming Wang; Jane A Branca; Harold D Chapman; Jing Zhu; Nina Donghia; Vivek Philip; William H Schott; Clive Wasserfall; Mark A Atkinson; Kevin D Mills; Caroline M Leeth; David V Serreze
Journal:  J Immunol       Date:  2017-05-01       Impact factor: 5.422

Review 7.  Targeting Type 1 Diabetes: Selective Approaches for New Therapies.

Authors:  Daniel F Sheehy; Sean P Quinnell; Arturo J Vegas
Journal:  Biochemistry       Date:  2019-01-17       Impact factor: 3.162

8.  Association of HLA-dependent islet autoimmunity with systemic antibody responses to intestinal commensal bacteria in children.

Authors:  Alexandra Paun; Christopher Yau; Shahab Meshkibaf; Michelle C Daigneault; Leili Marandi; Steven Mortin-Toth; Amit Bar-Or; Emma Allen-Vercoe; Philippe Poussier; Jayne S Danska
Journal:  Sci Immunol       Date:  2019-02-01

Review 9.  Trials in the prevention of type 1 diabetes: current and future.

Authors:  Diane K Wherrett
Journal:  Can J Diabetes       Date:  2014-08       Impact factor: 4.190

Review 10.  Type 1 diabetes.

Authors:  Mark A Atkinson; George S Eisenbarth; Aaron W Michels
Journal:  Lancet       Date:  2013-07-26       Impact factor: 79.321
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