Literature DB >> 20723168

Implementing a program to improve compliance with neonatal intensive care unit transfusion guidelines was accompanied by a reduction in transfusion rate: a pre-post analysis within a multihospital health care system.

Vickie L Baer1, Erick Henry, Diane K Lambert, Ronald A Stoddard, Susan E Wiedmeier, Larry D Eggert, Sarah Ilstrup, Robert D Christensen.   

Abstract

BACKGROUND: We previously reported that in the year 2006, approximately 35% of the transfusions administered in the Intermountain Healthcare neonatal intensive care units (NICU) were noncompliant with our transfusion guidelines. In January 2009 we instituted an electronic NICU transfusion ordering and monitoring system as part of a new program to improve compliance with transfusion guidelines. STUDY DESIGN AND METHODS: In the four largest NICUs of Intermountain Healthcare, we performed a pre-post analysis of compliance with transfusion guidelines and transfusion usage.
RESULTS: After beginning the new transfusion compliance program all four NICUs had an increase in compliance from 65% to 90%. Accompanying the improved compliance, all four NICUs had a reduction in transfusions administered. Specifically, compared with 2007 and 2008, there were 984 fewer NICU transfusions given in 2009. This included 554 fewer red blood cell (RBC) transfusions, 174 fewer platelet transfusions, and 256 fewer frozen plasma infusions. We calculate that in 2009, a total of 200 NICU patients who in previous years would have received one or more transfusions instead received none. Applying specific Intermountain Healthcare billing data to the observed transfusion reductions, this new program resulted in an annual decrease of $780,074 in blood bank charges (blood administration charges were not included). During the 3-year period, January 2007 through December 2009, we detected no change in NICU demographics, major morbidities, length of hospital stay, or mortality rate.
CONCLUSION: Implementing a systemwide NICU program to improve compliance with already-established transfusion guidelines increased compliance from 65% to 90%. Improved compliance with transfusion guidelines was accompanied by a significant reduction in transfusions given, with no increase in NICU length of stay or mortality rate.
© 2010 American Association of Blood Banks.

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Year:  2010        PMID: 20723168     DOI: 10.1111/j.1537-2995.2010.02823.x

Source DB:  PubMed          Journal:  Transfusion        ISSN: 0041-1132            Impact factor:   3.157


  18 in total

Review 1.  Recommendations for transfusion therapy in neonatology.

Authors:  Gabriella Girelli; Stefano Antoncecchi; Anna Maria Casadei; Antonio Del Vecchio; Paola Isernia; Mario Motta; Daniela Regoli; Costantino Romagnoli; Gino Tripodi; Claudio Velati
Journal:  Blood Transfus       Date:  2015-07       Impact factor: 3.443

2.  Evaluation of RBC Transfusion Practice in Adult ICUs and the Effect of Restrictive Transfusion Protocols on Routine Care.

Authors:  Kevin P Seitz; Jonathan E Sevransky; Greg S Martin; John D Roback; David J Murphy
Journal:  Crit Care Med       Date:  2017-02       Impact factor: 7.598

3.  Why do four NICUs using identical RBC transfusion guidelines have different gestational age-adjusted RBC transfusion rates?

Authors:  E Henry; R D Christensen; M J Sheffield; L D Eggert; P D Carroll; S D Minton; D K Lambert; S J Ilstrup
Journal:  J Perinatol       Date:  2014-09-25       Impact factor: 2.521

4.  Computerised decision support systems to promote appropriate use of blood products.

Authors:  Sheila A Fisher; Annemarie B Docherty; Carolyn Doree; Stephen P Hibbs; Michael F Murphy; Lise J Estcourt
Journal:  Cochrane Database Syst Rev       Date:  2017-02

5.  Plasma and Platelet Transfusion Strategies in Critically Ill Children Following Severe Trauma, Traumatic Brain Injury, and/or Intracranial Hemorrhage: From the Transfusion and Anemia EXpertise Initiative-Control/Avoidance of Bleeding.

Authors:  Robert Russell; David F Bauer; Susan M Goobie; Thorsten Haas; Marianne E Nellis; Daniel K Nishijima; Adam M Vogel; Jacques Lacroix
Journal:  Pediatr Crit Care Med       Date:  2022-01-01       Impact factor: 3.624

6.  Thrombocytopenia in Small-for-Gestational-Age Infants.

Authors:  Robert D Christensen; Vickie L Baer; Erick Henry; Gregory L Snow; Allison Butler; Martha C Sola-Visner
Journal:  Pediatrics       Date:  2015-08       Impact factor: 7.124

7.  A randomized, masked, placebo-controlled study of darbepoetin alfa in preterm infants.

Authors:  Robin K Ohls; Robert D Christensen; Beena D Kamath-Rayne; Adam Rosenberg; Susan E Wiedmeier; Mahshid Roohi; Conra Backstrom Lacy; Diane K Lambert; Jill J Burnett; Barbara Pruckler; Ron Schrader; Jean R Lowe
Journal:  Pediatrics       Date:  2013-06-17       Impact factor: 7.124

Review 8.  Transfusion-associated necrotizing enterocolitis: evidence and uncertainty.

Authors:  Sheila M Gephart
Journal:  Adv Neonatal Care       Date:  2012-08       Impact factor: 1.968

9.  Recommendations on RBC Transfusion in General Critically Ill Children Based on Hemoglobin and/or Physiologic Thresholds From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative.

Authors:  Allan Doctor; Jill M Cholette; Kenneth E Remy; Andrew Argent; Jeffrey L Carson; Stacey L Valentine; Scot T Bateman; Jacques Lacroix
Journal:  Pediatr Crit Care Med       Date:  2018-09       Impact factor: 3.624

10.  Variation in Neonatal Transfusion Practice.

Authors:  Ravi M Patel; Jeanne E Hendrickson; Marianne E Nellis; Rebecca Birch; Ruchika Goel; Oliver Karam; Matthew S Karafin; Sheila J Hanson; Bruce S Sachais; Ronald George Hauser; Naomi L C Luban; Jerome Gottschall; Cassandra D Josephson; Martha Sola-Visner
Journal:  J Pediatr       Date:  2021-04-07       Impact factor: 6.314

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