Literature DB >> 20721763

Modelling the effects of condom use and antiretroviral therapy in controlling HIV/AIDS among heterosexuals, homosexuals and bisexuals.

Noble Malunguza1, Steady Mushayabasa, Christinah Chiyaka, Zindoga Mukandavire.   

Abstract

A deterministic compartmental sex-structured HIV/AIDS model for assessing the effects of homosexuals and bisexuals in heterosexual settings in which homosexuality and bisexuality issues have remained taboo is presented. We extend the model to focus on the effects of condom use as a single strategy approach in HIV prevention in the absence of any other intervention strategies. Initially, we model the use of male condoms, followed by incorporating the use of both the female and male condoms. The model includes two primary factors in condom use to control HIV which are condom efficacy and compliance. Reproductive numbers for these models are computed and compared to assess the effectiveness of male and female condom use in a community. We also extend the basic model to consider the effects of antiretroviral therapy as a single strategy. The results from the study show that condoms can reduce the number of secondary infectives and thus can slow the development of the HIV/AIDS epidemic. Further, we note from the study that treatment of AIDS patients may enlarge the epidemic when the treatment drugs are not 100% effective and when treated AIDS patients indulge in risky sexual behaviour. Thus, the treatment with amelioration of AIDS patients should be accompanied with intense public health educational programs, which are capable of changing the attitude of treated AIDS patients towards safe sex. It is also shown from the study that the use of condoms in settings with the treatment may help in reducing the number of secondary infections thus slowing the epidemic.

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Year:  2010        PMID: 20721763     DOI: 10.1080/17486700903325167

Source DB:  PubMed          Journal:  Comput Math Methods Med        ISSN: 1748-670X            Impact factor:   2.238


  5 in total

1.  "I can't use a condom, I am a Christian:" salvation, death, and… naivety in Africa.

Authors:  Adamson S Muula
Journal:  Croat Med J       Date:  2010-10       Impact factor: 1.351

Review 2.  Mathematical models for the study of HIV spread and control amongst men who have sex with men.

Authors:  Narat Punyacharoensin; William John Edmunds; Daniela De Angelis; Richard Guy White
Journal:  Eur J Epidemiol       Date:  2011-09-20       Impact factor: 8.082

3.  Dynamic mathematical models of HIV/AIDS transmission in China.

Authors:  Jun-jie Wang; Kathleen Heather Reilly; Jing Luo; Chun-peng Zang; Ning Wang
Journal:  Chin Med J (Engl)       Date:  2010-08-05       Impact factor: 2.628

4.  Modeling schistosomiasis and HIV/AIDS codynamics.

Authors:  S Mushayabasa; C P Bhunu
Journal:  Comput Math Methods Med       Date:  2011-02-13       Impact factor: 2.238

5.  The importance of choice disability and structural intervention in the HIV epidemic in Sub-Saharan Africa.

Authors:  Rebecca de Boer; Jeffrey Musgrave; Neil Andersson; Frithjof Lutscher
Journal:  PLoS One       Date:  2017-04-11       Impact factor: 3.240

  5 in total

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