Literature DB >> 20720060

Molecular imaging of the dopamine transporter.

Andrea Varrone1, Christer Halldin.   

Abstract

The dopamine transporter (DAT) is a transmembrane protein responsible for reuptake of dopamine from the synaptic cleft and termination of dopaminergic transmission. Several radioligands are available for DAT imaging with SPECT and PET. This review summarizes the main SPECT and PET radioligands and the main applications of DAT imaging in neuropsychiatric disorders.

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Year:  2010        PMID： 20720060     DOI： 10.2967/jnumed.109.065656

Source DB:  PubMed          Journal:  J Nucl Med        ISSN： 0161-5505            Impact factor:   10.057


  28 in total

1.  Association of the ZFPM2 gene with antipsychotic-induced parkinsonism in schizophrenia patients.

Authors:  Lior Greenbaum; Robert C Smith; Mordechai Lorberboym; Anna Alkelai; Polina Zozulinsky; Tzuri Lifschytz; Tzuri Lifshytz; Yoav Kohn; Ruth Djaldetti; Bernard Lerer
Journal:  Psychopharmacology (Berl)       Date:  2011-09-24       Impact factor: 4.530

Review 2.  Applying imaging genetics to ADHD: the promises and the challenges.

Authors:  Zhaomin Wu; Li Yang; Yufeng Wang
Journal:  Mol Neurobiol       Date:  2014-04-01       Impact factor: 5.590

3.  Striatal presynaptic dopamine in schizophrenia, Part I: meta-analysis of dopamine active transporter (DAT) density.

Authors:  Paolo Fusar-Poli; Andreas Meyer-Lindenberg
Journal:  Schizophr Bull       Date:  2012-01-26       Impact factor: 9.306

Review 4.  Modeling of PET data in CNS drug discovery and development.

Authors:  Katarina Varnäs; Andrea Varrone; Lars Farde
Journal:  J Pharmacokinet Pharmacodyn       Date:  2013-05-10       Impact factor: 2.745

5.  Development and screening of contrast agents for in vivo imaging of Parkinson's disease.

Authors:  Krista L Neal; Naomi B Shakerdge; Steven S Hou; William E Klunk; Chester A Mathis; Evgueni E Nesterov; Timothy M Swager; Pamela J McLean; Brian J Bacskai
Journal:  Mol Imaging Biol       Date:  2013-10       Impact factor: 3.488

6.  Gastrodin ameliorates memory deficits in 3,3'-iminodipropionitrile-induced rats: possible involvement of dopaminergic system.

Authors:  Xiaona Wang; Shaofeng Yan; Aiqin Wang; Yanli Li; Feng Zhang
Journal:  Neurochem Res       Date:  2014-05-20       Impact factor: 3.996

Review 7.  Genetic targeting of the amphetamine and methylphenidate-sensitive dopamine transporter: on the path to an animal model of attention-deficit hyperactivity disorder.

Authors:  Marc A Mergy; Raajaram Gowrishankar; Gwynne L Davis; Tammy N Jessen; Jane Wright; Gregg D Stanwood; Maureen K Hahn; Randy D Blakely
Journal:  Neurochem Int       Date:  2013-12-08       Impact factor: 3.921

8.  Neuroprotective Activities of Spirulina platensis in the 6-OHDA Model of Parkinson's Disease Are Related to Its Anti-Inflammatory Effects.

Authors:  Francisco Arnaldo Viana Lima; Ivan Pinheiro Joventino; Francisca Pinheiro Joventino; Aline Cordeiro de Almeida; Kelly Rose Tavares Neves; Marta Regina do Carmo; Luzia Kalyne Almeida Moreira Leal; Geanne Matos de Andrade; Glauce Socorro de Barros Viana
Journal:  Neurochem Res       Date:  2017-08-31       Impact factor: 3.996

9.  Melatonin inhibits manganese-induced motor dysfunction and neuronal loss in mice: involvement of oxidative stress and dopaminergic neurodegeneration.

Authors:  Yu Deng; Congcong Jiao; Chao Mi; Bin Xu; Yuehui Li; Fei Wang; Wei Liu; Zhaofa Xu
Journal:  Mol Neurobiol       Date:  2014-06-28       Impact factor: 5.590

10.  An efficient synthesis of dopamine transporter tracer [¹⁸F]FECNT.

Authors:  D Murali; T E Barnhart; N T Vandehey; B T Christian; R J Nickles; A K Converse; J A Larson; J E Holden; M L Schneider; O T Dejesus
Journal:  Appl Radiat Isot       Date:  2012-10-23       Impact factor: 1.513
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