Literature DB >> 20719506

Structure-activity relationship study of glaziovianin A against cell cycle progression and spindle formation of HeLa S3 cells.

Akiyuki Ikedo1, Ichiro Hayakawa, Takeo Usui, Sayaka Kazami, Hiroyuki Osada, Hideo Kigoshi.   

Abstract

Various derivatives of glaziovianin A, an antitumor isoflavone, were synthesized, and the cytotoxicity of each against HeLa S3 cells was investigated. Compared to glaziovianin A, the O7-allyl derivative was found to be more cytotoxic against HeLa S3 cells and a more potent M-phase inhibitor. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 20719506     DOI： 10.1016/j.bmcl.2010.07.111

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

1.  Structure Optimization of Gatastatin for the Development of γ-Tubulin-Specific Inhibitor.

Authors:  Kana Shintani; Haruna Ebisu; Minagi Mukaiyama; Taisei Hatanaka; Takumi Chinen; Daisuke Takao; Yoko Nagumo; Akira Sakakura; Ichiro Hayakawa; Takeo Usui
Journal:  ACS Med Chem Lett       Date:  2020-03-30       Impact factor: 4.345

Review 2.  Application of the Suzuki-Miyaura reaction in the synthesis of flavonoids.

Authors:  Mamoalosi A Selepe; Fanie R Van Heerden
Journal:  Molecules       Date:  2013-04-22       Impact factor: 4.411
  2 in total

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