Literature DB >> 20717681

[Molecular pathology of thyroid tumors].

K W Schmid1.   

Abstract

Molecular genetic analysis is gaining in significance for the differential diagnosis of thyroid tumours. Identifying specific mutations and/or rearrangements offers not only the possibility to distinguish benign from malignant tumours, but also to classify thyroid malignancies more precisely, which can have a substantial influence on the clinical management of patients. In recent years expression analysis of micro-RNA (miRNA) has become an additional tool to improve diagnostic accuracy in thyroid tumours. In addition to its diagnostic contribution, molecular genetic evaluation of thyroid tumours has significantly deepened our understanding of the development, progression and therapy of these tumours.

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Year:  2010        PMID： 20717681     DOI： 10.1007/s00292-010-1321-2

Source DB:  PubMed          Journal:  Pathologe        ISSN： 0172-8113            Impact factor:   1.011


  32 in total

1.  Interobserver and intraobserver reproducibility in the histopathology of follicular thyroid carcinoma.

Authors:  Brigitte Franc; Pauline de la Salmonière; Françoise Lange; Catherine Hoang; Albert Louvel; Anne de Roquancourt; Françoise Vildé; Gilles Hejblum; Sylvie Chevret; Claude Chastang
Journal:  Hum Pathol       Date:  2003-11       Impact factor: 3.466

2.  Analysis of deregulated miRNAs is helpful to distinguish poorly differentiated thyroid carcinoma from papillary thyroid carcinoma.

Authors:  S Schwertheim; S-Y Sheu; K Worm; F Grabellus; K W Schmid
Journal:  Horm Metab Res       Date:  2009-04-15       Impact factor: 2.936

3.  The role of microRNA genes in papillary thyroid carcinoma.

Authors:  Huiling He; Krystian Jazdzewski; Wei Li; Sandya Liyanarachchi; Rebecca Nagy; Stefano Volinia; George A Calin; Chang-Gong Liu; Kaarle Franssila; Saul Suster; Richard T Kloos; Carlo M Croce; Albert de la Chapelle
Journal:  Proc Natl Acad Sci U S A       Date:  2005-12-19       Impact factor: 11.205

Review 4.  Histogenesis of thyroid C-cell carcinoma.

Authors:  H R Harach
Journal:  Curr Top Pathol       Date:  1997

5.  Sporadic versus familial medullary thyroid microcarcinoma: a histopathologic study of 50 consecutive patients.

Authors:  K Kaserer; C Scheuba; N Neuhold; A Weinhäusel; O A Haas; H Vierhapper; B Niederle
Journal:  Am J Surg Pathol       Date:  2001-10       Impact factor: 6.394

6.  RAS point mutations and PAX8-PPAR gamma rearrangement in thyroid tumors: evidence for distinct molecular pathways in thyroid follicular carcinoma.

Authors:  Marina N Nikiforova; Roy A Lynch; Paul W Biddinger; Erik K Alexander; Gerald W Dorn; Giovanni Tallini; Todd G Kroll; Yuri E Nikiforov
Journal:  J Clin Endocrinol Metab       Date:  2003-05       Impact factor: 5.958

7.  FOXO3a: a novel player in thyroid carcinogenesis?

Authors:  Stefan Karger; Carl Weidinger; Kerstin Krause; Sien-Yi Sheu; Thomas Aigner; Oliver Gimm; Kurt-Werner Schmid; Henning Dralle; Dagmar Fuhrer
Journal:  Endocr Relat Cancer       Date:  2008-10-09       Impact factor: 5.678

Review 8.  Intragenic mutations in thyroid cancer.

Authors:  Manuel Sobrinho-Simões; Valdemar Máximo; Ana Sofia Rocha; Vitor Trovisco; Patricia Castro; Ana Preto; Jorge Lima; Paula Soares
Journal:  Endocrinol Metab Clin North Am       Date:  2008-06       Impact factor: 4.741

Review 9.  An evidence-based approach to familial nonmedullary thyroid cancer: screening, clinical management, and follow-up.

Authors:  Rebecca S Sippel; Nadine R Caron; Orlo H Clark
Journal:  World J Surg       Date:  2007-05       Impact factor: 3.352

Review 10.  Molecular genetics of thyroid cancer: implications for diagnosis, treatment and prognosis.

Authors:  Marina N Nikiforova; Yuri E Nikiforov
Journal:  Expert Rev Mol Diagn       Date:  2008-01       Impact factor: 5.225
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  5 in total

Review 1.  [MicroRNA profiles in fine needle biopsy of the thyroid].

Authors:  S Ting; S-Y Sheu-Grabellus; K Worm; K W Schmid
Journal:  Pathologe       Date:  2012-07       Impact factor: 1.011

2.  Dissecting molecular events in thyroid neoplasia provides evidence for distinct evolution of follicular thyroid adenoma and carcinoma.

Authors:  Kerstin Krause; Susanne Prawitt; Markus Eszlinger; Christian Ihling; Andrea Sinz; Katrin Schierle; Oliver Gimm; Henning Dralle; Frank Steinert; Sien-Yi Sheu; Kurt W Schmid; Dagmar Fuhrer
Journal:  Am J Pathol       Date:  2011-10-06       Impact factor: 4.307

3.  [Medullary thyroid carcinoma].

Authors:  V Tiedje; S Ting; H Dralle; K W Schmid; D Führer
Journal:  Internist (Berl)       Date:  2015-09       Impact factor: 0.743

4.  Pathogenic mechanisms of deregulated microRNA expression in thyroid carcinomas of follicular origin.

Authors:  Juliane Braun; Stefan Hüttelmaier
Journal:  Thyroid Res       Date:  2011-08-03

5.  New insights into intranuclear inclusions in thyroid carcinoma: Association with autophagy and with BRAFV600E mutation.

Authors:  Suzan Schwertheim; Sarah Theurer; Holger Jastrow; Thomas Herold; Saskia Ting; Daniela Westerwick; Stefanie Bertram; Christoph M Schaefer; Julia Kälsch; Hideo A Baba; Kurt W Schmid
Journal:  PLoS One       Date:  2019-12-16       Impact factor: 3.240
  5 in total

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