Literature DB >> 2071761

HM-PAO-SPECT in persistent vegetative state after head injury: prognostic indicator of the likelihood of recovery?

W Oder1, G Goldenberg, I Podreka, L Deecke.   

Abstract

Management of patients presenting with traumatic persistent vegetative state (PVS) calls for extensive resources. The ability to predict whether or not a patient is likely to recover is a critical issue. In 12 patients with PVS admitted consecutively for early rehabilitation after head injury, pattern of brain activity was measured by 99mTc-hexamethyl-propylenamineoxime (99mTc-HM-PAO) brain SPECT (single photon emission computer tomography). All patients were re-investigated after a mean observation period of 3 years. A global reduction of cortical blood flow was a reliable predictor of poor long-term outcome, but the demonstration of only focal deficits did not reliably indicate a favourable outcome. Brain SPECT may help to improve outcome prediction in patients with traumatic PVS.

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Year:  1991        PMID： 2071761     DOI： 10.1007/BF01704718

Source DB:  PubMed          Journal:  Intensive Care Med        ISSN： 0342-4642            Impact factor:   17.440


  38 in total

1.  Diffuse degeneration of the cerebral white matter in severe dementia following head injury.

Authors:  S J STRICH
Journal:  J Neurol Neurosurg Psychiatry       Date:  1956-08       Impact factor: 10.154

2.  Prognosis in patients with severe head injury.

Authors:  B Jennett; G Teasdale; S Galbraith; R Braakman; C Avezaat; J Minderhoud; J Heiden; T Kurze; G Murray; L Parker
Journal:  Acta Neurochir Suppl (Wien)       Date:  1979

3.  Early and late magnetic resonance imaging and neuropsychological outcome after head injury.

Authors:  J T Wilson; K D Wiedmann; D M Hadley; B Condon; G Teasdale; D N Brooks
Journal:  J Neurol Neurosurg Psychiatry       Date:  1988-03       Impact factor: 10.154

4.  Improved outcome prediction based on CSF extrapolated creatine kinase BB isoenzyme activity and other risk factors in severe head injury.

Authors:  P Hans; A Albert; C Franssen; J Born
Journal:  J Neurosurg       Date:  1989-07       Impact factor: 5.115

5.  The Walter J. Zeiter lecture. Considerations for management of the persistent vegetative state.

Authors:  S Berrol
Journal:  Arch Phys Med Rehabil       Date:  1986-05       Impact factor: 3.966

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Authors:  B Jennett; F Plum
Journal:  Lancet       Date:  1972-04-01       Impact factor: 79.321

7.  Initial experience with technetium-99m HM-PAO brain SPECT.

Authors:  I Podreka; E Suess; G Goldenberg; M Steiner; T Brücke; C Müller; W Lang; R D Neirinckx; L Deecke
Journal:  J Nucl Med       Date:  1987-11       Impact factor: 10.057

8.  Head injury: early results of comparing CT and high-field MR.

Authors:  R A Zimmerman; L T Bilaniuk; D B Hackney; H I Goldberg; R I Grossman
Journal:  AJR Am J Roentgenol       Date:  1986-12       Impact factor: 3.959

9.  Technetium-99m d,l-HM-PAO: a new radiopharmaceutical for SPECT imaging of regional cerebral blood perfusion.

Authors:  R D Neirinckx; L R Canning; I M Piper; D P Nowotnik; R D Pickett; R A Holmes; W A Volkert; A M Forster; P S Weisner; J A Marriott
Journal:  J Nucl Med       Date:  1987-02       Impact factor: 10.057

10.  Relation of cerebral blood flow to neurological status and outcome in head-injured patients.

Authors:  W D Obrist; T A Gennarelli; H Segawa; C A Dolinskas; T W Langfitt
Journal:  J Neurosurg       Date:  1979-09       Impact factor: 5.115
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1.  Epidemiology and prognosis of coma in daytime television dramas.

Authors:  David Casarett; Jessica M Fishman; Holly Jo MacMoran; Amy Pickard; David A Asch
Journal:  BMJ       Date:  2005-12-24

2.  Single photon emission computed tomography scanning: A predictor of outcome in vegetative state of head injury.

Authors:  Pralaya Nayak; Ashok K Mahapatra
Journal:  J Neurosci Rural Pract       Date:  2011-01
  2 in total

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