Literature DB >> 20717583

DNA photocleavage by an osmium(II) complex in the PDT window.

Yujie Sun1, Lauren E Joyce, Nicole M Dickson, Claudia Turro.   

Abstract

The extended pi-delocalization of dppn (benzo[i]dipyrido[3,2-a:2,3-c]phenazine) results in a (3)pipi* state as the lowest triplet excited state in [Os(bpy)(2)(dppn)](2+) (bpy = 2,2'-bipyridine), which generates a (1)O(2) quantum yield of 0.42. Together with its (3)MLCT absorption, this new osmium complex shows efficient DNA cleavage under irradiation of lambda(irr) > or = 645 nm.

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Year:  2010        PMID： 20717583     DOI： 10.1039/c0cc02571b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

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3.  [Ru(bpy)2(5-cyanouracil)2]2+ as a potential light-activated dual-action therapeutic agent.

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Journal:  Inorg Chem       Date:  2011-08-31       Impact factor: 5.165

4.  A Photosensitizer-Loaded DNA Origami Nanosystem for Photodynamic Therapy.

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Journal:  ACS Nano       Date:  2016-03-10       Impact factor: 15.881

Review 5.  Target-directed catalytic metallodrugs.

Authors:  J C Joyner; J A Cowan
Journal:  Braz J Med Biol Res       Date:  2013-07-02       Impact factor: 2.590

6.  Photophysical Properties and DNA Binding of Two Intercalating Osmium Polypyridyl Complexes Showing Light-Switch Effects.

Authors:  Mark Stitch; Rayhaan Z Boota; Alannah S Chalkley; Tony D Keene; Jeremy C Simpson; Paul A Scattergood; Paul I P Elliott; Susan J Quinn
Journal:  Inorg Chem       Date:  2022-09-12       Impact factor: 5.436

7.  Synthesis and In Vitro Antitumor Activity of Two Mixed-Ligand Oxovanadium(IV) Complexes of Schiff Base and Phenanthroline.

Authors:  Yongli Zhang; Xiangsheng Wang; Wei Fang; Xiaoyan Cai; Fujiang Chu; Xiangwen Liao; Jiazheng Lu
Journal:  Bioinorg Chem Appl       Date:  2013-01-29       Impact factor: 7.778

8.  Intracellular Photophysics of an Osmium Complex bearing an Oligothiophene Extended Ligand.

Authors:  Kilian R A Schneider; Avinash Chettri; Houston D Cole; Katharina Reglinski; Jannik Brückmann; John A Roque; Anne Stumper; Djawed Nauroozi; Sylvia Schmid; Christoffer B Lagerholm; Sven Rau; Peter Bäuerle; Christian Eggeling; Colin G Cameron; Sherri A McFarland; Benjamin Dietzek
Journal:  Chemistry       Date:  2020-10-14       Impact factor: 5.020
  8 in total

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