Literature DB >> 20716967

Nutlin's two roads toward apoptosis.

Qi Zhang1, Hua Lu.   

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Year:  2010        PMID: 20716967      PMCID: PMC3040947          DOI: 10.4161/cbt.10.6.13127

Source DB:  PubMed          Journal:  Cancer Biol Ther        ISSN: 1538-4047            Impact factor:   4.742


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  27 in total

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2.  c-Myc and caspase-2 are involved in activating Bax during cytotoxic drug-induced apoptosis.

Authors:  Xuefang Cao; Richard L Bennett; W Stratford May
Journal:  J Biol Chem       Date:  2008-03-28       Impact factor: 5.157

3.  Molecular mechanisms of nutlin-induced apoptosis in multiple myeloma: evidence for p53-transcription-dependent and -independent pathways.

Authors:  Manujendra N Saha; Hua Jiang; Hong Chang
Journal:  Cancer Biol Ther       Date:  2010-10-01       Impact factor: 4.742

4.  MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy.

Authors:  Kensuke Kojima; Marina Konopleva; Ismael J Samudio; Masato Shikami; Maria Cabreira-Hansen; Teresa McQueen; Vivian Ruvolo; Twee Tsao; Zhihong Zeng; Lyubomir T Vassilev; Michael Andreeff
Journal:  Blood       Date:  2005-07-12       Impact factor: 22.113

5.  c-Myc induces apoptosis in epithelial cells by both p53-dependent and p53-independent mechanisms.

Authors:  D Sakamuro; V Eviner; K J Elliott; L Showe; E White; G C Prendergast
Journal:  Oncogene       Date:  1995-12-07       Impact factor: 9.867

6.  Genetic determinants of p53-induced apoptosis and growth arrest.

Authors:  K Polyak; T Waldman; T C He; K W Kinzler; B Vogelstein
Journal:  Genes Dev       Date:  1996-08-01       Impact factor: 11.361

Review 7.  p53 moves to mitochondria: a turn on the path to apoptosis.

Authors:  Maureen E Murphy; J I-Ju Leu; Donna L George
Journal:  Cell Cycle       Date:  2004-07-04       Impact factor: 4.534

8.  Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase.

Authors:  D Yu; T Jing; B Liu; J Yao; M Tan; T J McDonnell; M C Hung
Journal:  Mol Cell       Date:  1998-11       Impact factor: 17.970

9.  Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukemia.

Authors:  Kensuke Kojima; Marina Konopleva; Teresa McQueen; Susan O'Brien; William Plunkett; Michael Andreeff
Journal:  Blood       Date:  2006-03-16       Impact factor: 22.113

10.  In vivo activation of the p53 pathway by small-molecule antagonists of MDM2.

Authors:  Lyubomir T Vassilev; Binh T Vu; Bradford Graves; Daisy Carvajal; Frank Podlaski; Zoran Filipovic; Norman Kong; Ursula Kammlott; Christine Lukacs; Christian Klein; Nader Fotouhi; Emily A Liu
Journal:  Science       Date:  2004-01-02       Impact factor: 47.728

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  1 in total

Review 1.  Targeting p53 by small molecules in hematological malignancies.

Authors:  Manujendra N Saha; Lugui Qiu; Hong Chang
Journal:  J Hematol Oncol       Date:  2013-03-27       Impact factor: 17.388

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