OBJECTIVE: The LupusQoL-US instrument was recently validated in the US. We studied the benchmarks for a US patient cohort with systemic lupus erythematosus (SLE) and relevant demographic and disease correlates. METHODS: LupusQoL-US was administered to 185 patients with SLE. Demographic data (age, sex, ethnicity, marital status) and disease features (duration, disease activity and damage) were assessed simultaneously. Descriptive statistics were obtained. LupusQoL-US domain scores were calculated, and compared by sex, ethnicity, and marital status using nonparametric tests. Correlation between LupusQoL-US domains and age, disease duration, disease activity, and disease damage were obtained. RESULTS: Mean age of patients was 42.2 +/- 14.5 years; 94% of subjects were women. African American patients comprised 60% of the study cohort. The most affected domains were Fatigue and Physical Health. The least affected was Intimate Relationships. Age correlated with Physical Health, Pain, and Body Image (r = 0.15-0.18). Differences were observed based on sex and marital status, but not by ethnicity; there the LupusQoL-US correlated inversely with disease activity (r = -0.001 to -0.36) and damage (r = -0.003 to -0.40). CONCLUSION: All domains of the LupusQoL-US based health related quality of life (HRQOL) were affected adversely. HRQOL varied by age, sex, and marital status in our SLE cohort.
OBJECTIVE: The LupusQoL-US instrument was recently validated in the US. We studied the benchmarks for a US patient cohort with systemic lupus erythematosus (SLE) and relevant demographic and disease correlates. METHODS: LupusQoL-US was administered to 185 patients with SLE. Demographic data (age, sex, ethnicity, marital status) and disease features (duration, disease activity and damage) were assessed simultaneously. Descriptive statistics were obtained. LupusQoL-US domain scores were calculated, and compared by sex, ethnicity, and marital status using nonparametric tests. Correlation between LupusQoL-US domains and age, disease duration, disease activity, and disease damage were obtained. RESULTS: Mean age of patients was 42.2 +/- 14.5 years; 94% of subjects were women. African American patients comprised 60% of the study cohort. The most affected domains were Fatigue and Physical Health. The least affected was Intimate Relationships. Age correlated with Physical Health, Pain, and Body Image (r = 0.15-0.18). Differences were observed based on sex and marital status, but not by ethnicity; there the LupusQoL-US correlated inversely with disease activity (r = -0.001 to -0.36) and damage (r = -0.003 to -0.40). CONCLUSION: All domains of the LupusQoL-US based health related quality of life (HRQOL) were affected adversely. HRQOL varied by age, sex, and marital status in our SLE cohort.
Authors: I Etchegaray-Morales; S Méndez-Martínez; C Jiménez-Hernández; C Mendoza-Pinto; N E Alonso-García; A Montiel-Jarquín; A López-Colombo; A García-Villaseñor; M H Cardiel; M García-Carrasco Journal: PLoS One Date: 2017-01-23 Impact factor: 3.240
Authors: Alvaro Gomez; Victor Qiu; Arvid Cederlund; Alexander Borg; Julius Lindblom; Sharzad Emamikia; Yvonne Enman; Jon Lampa; Ioannis Parodis Journal: Front Med (Lausanne) Date: 2021-04-16
Authors: Fhabián S Carrión-Nessi; María V Marcano-Rojas; Sinibaldo R Romero Arocha; Daniela L Mendoza Millán; David A Forero-Peña; Allen W Antuarez-Magallanes; Soham Al Snih; Martín A Rodríguez; Yurilís J Fuentes-Silva Journal: BMC Rheumatol Date: 2022-01-04