Literature DB >> 20716355

Hypothalamic abnormalities and Parkinsonism associated with H1N1 influenza infection.

Alejandra González-Duarte1, Lucía Magaña Zamora, Carlos Cantú Brito, Guillermo García-Ramos.   

Abstract

OBJECTIVE: To describe a case of a young adult with severe H1N1 influenza illness associated with hypothalamic abnormalities and post-influenza parkinsonism.
DESIGN: Case report. PATIENT: A 22-year-old woman with H1N1 influenza infection developed encephalopathy followed by diverse hypothalamic dysfunction manifestations, sleeplessness, and persistent parkinsonian features.
RESULTS: CSF analysis, brain imaging and EEG ruled out hypoxic brain injury or other illnesses.
CONCLUSIONS: A number of viruses have been associated with both acute and chronic parkinsonism. A link between parkinsonism and influenza viruses is somewhat controversial. This is the first reported case of parkinsonism following an H1N1 influenza infection.

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Mesh:

Year:  2010        PMID: 20716355      PMCID: PMC2933605          DOI: 10.1186/1742-2094-7-47

Source DB:  PubMed          Journal:  J Neuroinflammation        ISSN: 1742-2094            Impact factor:   8.322


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