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8 in total

1. Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor.

Authors: Sanil Bhatia; Viktoria Krieger; Michael Groll; Jeremy D Osko; Nina Reßing; Heinz Ahlert; Arndt Borkhardt; Thomas Kurz; David W Christianson; Julia Hauer; Finn K Hansen
Journal: J Med Chem Date: 2018-11-08 Impact factor: 7.446

2. Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome.

Authors: Hao-Chi Hsu; Pradeep K Singh; Hao Fan; Rong Wang; George Sukenick; Carl Nathan; Gang Lin; Huilin Li
Journal: Biochemistry Date: 2016-12-27 Impact factor: 3.162

3. Oxadiazole-isopropylamides as potent and noncovalent proteasome inhibitors.

Authors: Sevil Ozcan; Aslamuzzaman Kazi; Frank Marsilio; Bin Fang; Wayne C Guida; John Koomen; Harshani R Lawrence; Saïd M Sebti
Journal: J Med Chem Date: 2013-05-13 Impact factor: 7.446

4. Discovery of PI-1840, a novel noncovalent and rapidly reversible proteasome inhibitor with anti-tumor activity.

Authors: Aslamuzzaman Kazi; Sevil Ozcan; Awet Tecleab; Ying Sun; Harshani R Lawrence; Saïd M Sebti
Journal: J Biol Chem Date: 2014-02-25 Impact factor: 5.157

5. Blockade of the malignant phenotype by β-subunit selective noncovalent inhibition of immuno- and constitutive proteasomes.

Authors: Bruno O Villoutreix; Abdel-Majid Khatib; Yan Cheng; Maria A Miteva; Xavier Maréchal; Joëlle Vidal; Michèle Reboud-Ravaux
Journal: Oncotarget Date: 2017-02-07

20S proteasome inhibition: designing noncovalent linear peptide mimics of the natural product TMC-95A.

1. Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor.

2. Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome.

3. Oxadiazole-isopropylamides as potent and noncovalent proteasome inhibitors.

4. Discovery of PI-1840, a novel noncovalent and rapidly reversible proteasome inhibitor with anti-tumor activity.

5. Blockade of the malignant phenotype by β-subunit selective noncovalent inhibition of immuno- and constitutive proteasomes.

6. Natural product scaffolds as inspiration for the design and synthesis of 20S human proteasome inhibitors.

7. Inhibition of human and yeast 20S proteasome by analogues of trypsin inhibitor SFTI-1.

Review 8. Fungal Secondary Metabolites as Inhibitors of the Ubiquitin-Proteasome System.