Literature DB >> 2071364

Increased acetylcholine sensitivity in Duchenne muscular dystrophy myotubes.

G Meola1, E Mancinelli, L Geremia, G Scarlato.   

Abstract

Monolayer cultures were established from explants of muscle obtained from 6 patients with Duchenne muscular dystrophy (DMD) and 9 controls. Electrophysiological studies were made after 3-4 weeks in vitro, when many myotubes had formed. An intracellular electrode was used to record cell membrane potential, and acetylcholine was applied by ionophoresis. The myotubes grown from Duchenne muscle showed greater acetylcholine sensitivity than controls.

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Year:  1991        PMID： 2071364     DOI： 10.1007/BF02337031

Source DB:  PubMed          Journal:  Ital J Neurol Sci        ISSN： 0392-0461


  25 in total

1.  Voltage-dependent channels of human muscle cultures.

Authors:  A Trautmann; C Delaporte; A Marty
Journal:  Pflugers Arch       Date:  1986-02       Impact factor: 3.657

2.  Determination of dose-response curves by quantitative ionophoresis at the frog neuromuscular junction.

Authors:  F Dreyer; K Peper; R Sterz
Journal:  J Physiol       Date:  1978-08       Impact factor: 5.182

3.  Duchenne muscular dystrophy: deficiency of dystrophin at the muscle cell surface.

Authors:  E Bonilla; C E Samitt; A F Miranda; A P Hays; G Salviati; S DiMauro; L M Kunkel; E P Hoffman; L P Rowland
Journal:  Cell       Date:  1988-08-12       Impact factor: 41.582

4.  Immunocytochemical study of dystrophin in muscle cultures from patients with Duchenne muscular dystrophy and unaffected control patients.

Authors:  A F Miranda; E Bonilla; G Martucci; C T Moraes; A P Hays; S Dimauro
Journal:  Am J Pathol       Date:  1988-09       Impact factor: 4.307

5.  Myogenic defect in acetylcholinesterase regulation in muscular dystrophy of the chicken.

Authors:  T A Linkhart; G W Yee; B W Wilson
Journal:  Science       Date:  1975-02-14       Impact factor: 47.728

6.  Defective myoblasts identified in Duchenne muscular dystrophy.

Authors:  H M Blau; C Webster; G K Pavlath
Journal:  Proc Natl Acad Sci U S A       Date:  1983-08       Impact factor: 11.205

7.  Differentiation properties of pure populations of human dystrophic muscle cells.

Authors:  H M Blau; C Webster; C P Chiu; S Guttman; F Chandler
Journal:  Exp Cell Res       Date:  1983-04-01       Impact factor: 3.905

8.  Denervation changes in normal and myasthenia gravis human muscle fibres during organ culture.

Authors:  S G Cull-Candy; R Miledi; O D Uchitel
Journal:  J Physiol       Date:  1982-12       Impact factor: 5.182

9.  Mucolipidosis II (I-cell disease): studies of muscle biopsy and muscle cultures.

Authors:  S Shanske; A F Miranda; A S Penn; S DiMauro
Journal:  Pediatr Res       Date:  1981-10       Impact factor: 3.756

10.  Human myotube differentiation in vitro in different culture conditions.

Authors:  C Delaporte; B Dautreaux; M Fardeau
Journal:  Biol Cell       Date:  1986       Impact factor: 4.458
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  1 in total

Review 1.  Hereditary human myopathies in muscle culture.

Authors:  G Meola
Journal:  Ital J Neurol Sci       Date:  1991-06
  1 in total

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