Literature DB >> 20713554

On the methodology of drug trials in migraine with aura.

Anne Werner Hauge1, Anders Hougaard, Jes Olesen.   

Abstract

INTRODUCTION: Specific problems occur in clinical treatment trials for migraine with aura that differ from those encountered in treatment trials for migraine without aura. DISCUSSION: Based on our experience with four such trials, we point to a number of possible solutions and outline areas for future inquiry. We make recommendations about subject selection; the choice, definition and assessment of outcome measures; optimal treatments in relation to aura and headache; and we provide samples of study report forms used to record occurrence of aura and headache in this population.

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Year:  2010        PMID： 20713554     DOI： 10.1177/0333102409359091

Source DB:  PubMed          Journal:  Cephalalgia        ISSN： 0333-1024            Impact factor:   6.292


  5 in total

Review 1.  Episodic Migraine With and Without Aura: Key Differences and Implications for Pathophysiology, Management, and Assessing Risks.

Authors:  Angeliki Vgontzas; Rebecca Burch
Journal:  Curr Pain Headache Rep       Date:  2018-10-05

Review 2.  Are the current IHS guidelines for migraine drug trials being followed?

Authors:  Anders Hougaard; Peer Tfelt-Hansen
Journal:  J Headache Pain       Date:  2010-10-08       Impact factor: 7.277

3.  Frovatriptan versus zolmitriptan for the acute treatment of migraine with aura: a subgroup analysis of a double-blind, randomized, multicenter, Italian study.

Authors:  Vincenzo Tullo; Gianni Allais; Marcella Curone; Michel D Ferrari; Stefano Omboni; Chiara Benedetto; Bruno Colombo; Dario Zava; Gennaro Bussone
Journal:  Neurol Sci       Date:  2012-05       Impact factor: 3.307

4.  Guidelines of the International Headache Society for controlled trials of acute treatment of migraine attacks in adults: Fourth edition.

Authors:  Hans-Christoph Diener; Cristina Tassorelli; David W Dodick; Stephen D Silberstein; Richard B Lipton; Messoud Ashina; Werner J Becker; Michel D Ferrari; Peter J Goadsby; Patricia Pozo-Rosich; Shuu-Jiun Wang; Jay Mandrekar
Journal:  Cephalalgia       Date:  2019-02-26       Impact factor: 6.292

Review 5.  Differences in treatment response between migraine with aura and migraine without aura: lessons from clinical practice and RCTs.

Authors:  Jakob Møller Hansen; Andrew Charles
Journal:  J Headache Pain       Date:  2019-09-06       Impact factor: 7.277
  5 in total

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