Literature DB >> 20711764

Co-morbid PTSD and suicidality in individuals with schizophrenia and substance and alcohol abuse.

Nicholas Tarrier1, Alicia Picken.   

Abstract

BACKGROUND: Suicide risk is high in schizophrenic patients and is further elevated in dual diagnosis patients. Suicide behaviour is a continuum from ideation, plans to attempts. Exposure to traumatic stress and co-morbid PTSD is elevated in schizophrenic patients. Suicide behaviour is also common in non-psychotic PTSD patients. This study aimed to investigate the effect of trauma and co-morbid PTSD on suicide behaviour in dual diagnosis patients and whether co-morbid PTSD would further elevate suicide risk.
METHOD: This was a cross-sectional study in which suicide behaviour was compared in those with and without co-morbid PTSD in 110 patients suffering schizophrenia and alcohol and/or substance abuse.
RESULTS: 100 (91%) reported at least one traumatic event with an average of 4.3 events. 31 (28%) patients met criteria for full PTSD. Current suicidal ideation was reported by 39 (35%) and 23 (21%) reported plans and ideation, 69 (63%) reported at least one previous suicide attempt. Suicide behaviour was significantly associated with an increasing number of traumatic events. Suicidality was significantly associated and elevated with co-morbid PTSD. Analysis indicated that the effect of trauma on suicide behaviour appeared to be mediated by hopelessness.
CONCLUSIONS: Suicide behaviour was not associated with exposure to trauma per se but was associated with incremental exposure to traumatic experiences. Consistent with the study hypotheses, co-morbid PTSD further adds to the risk of suicide behaviour in an already vulnerable group.

Entities:  

Mesh:

Year:  2010        PMID: 20711764     DOI: 10.1007/s00127-010-0277-0

Source DB:  PubMed          Journal:  Soc Psychiatry Psychiatr Epidemiol        ISSN: 0933-7954            Impact factor:   4.328


  53 in total

Review 1.  Psychosocial approaches to dual diagnosis.

Authors:  R E Drake; K T Mueser
Journal:  Schizophr Bull       Date:  2000       Impact factor: 9.306

Review 2.  Psychological vulnerability to completed suicide: a review of empirical studies.

Authors:  K R Conner; P R Duberstein; Y Conwell; L Seidlitz; E D Caine
Journal:  Suicide Life Threat Behav       Date:  2001

3.  Early insight predicts depression and attempted suicide after 4 years in first-episode schizophrenia and schizophreniform disorder.

Authors:  N Crumlish; P Whitty; M Kamali; M Clarke; S Browne; O McTigue; A Lane; A Kinsella; C Larkin; E O'Callaghan
Journal:  Acta Psychiatr Scand       Date:  2005-12       Impact factor: 6.392

4.  The subjective consequences of suffering a first episode psychosis: trauma and suicide behaviour.

Authors:  Nicholas Tarrier; Sobia Khan; Joanne Cater; Alicia Picken
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2006-11-02       Impact factor: 4.328

5.  Psychometric evaluation of trauma and posttraumatic stress disorder assessments in persons with severe mental illness.

Authors:  K T Mueser; M P Salyers; S D Rosenberg; J D Ford; L Fox; P Carty
Journal:  Psychol Assess       Date:  2001-03

6.  Comorbidity of substance misuse and mental illness in community mental health and substance misuse services.

Authors:  T Weaver; P Madden; V Charles; G Stimson; A Renton; P Tyrer; T Barnes; C Bench; H Middleton; N Wright; S Paterson; W Shanahan; N Seivewright; C Ford
Journal:  Br J Psychiatry       Date:  2003-10       Impact factor: 9.319

7.  The lifetime risk of suicide in schizophrenia: a reexamination.

Authors:  Brian A Palmer; V Shane Pankratz; John Michael Bostwick
Journal:  Arch Gen Psychiatry       Date:  2005-03

8.  Specificity of the Calgary Depression Scale for schizophrenics.

Authors:  D Addington; J Addington; E Maticka-Tyndale
Journal:  Schizophr Res       Date:  1994-02       Impact factor: 4.939

9.  Suicide attempts of high medical seriousness in schizophrenic patients.

Authors:  E Nieto; E Vieta; C Gastó; J Vallejo; E Cirera
Journal:  Compr Psychiatry       Date:  1992 Nov-Dec       Impact factor: 3.735

10.  Suicide schema in schizophrenia: the effect of emotional reactivity, negative symptoms and schema elaboration.

Authors:  Nicholas Tarrier; Patricia Gooding; Lynsey Gregg; Judith Johnson; Richard Drake
Journal:  Behav Res Ther       Date:  2007-03-18
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  11 in total

1.  Trauma exposure and PTSD in women with schizophrenia and coexisting substance use disorders: comparisons to women with severe depression and substance use disorders.

Authors:  Jennifer M Aakre; Clayton H Brown; Kathleen M Benson; Amy L Drapalski; Jean S Gearon
Journal:  Psychiatry Res       Date:  2014-12-30       Impact factor: 3.222

2.  The effect of risky alcohol use and smoking on suicide risk: findings from the German MONICA/KORA-Augsburg Cohort Study.

Authors:  Barbara Schneider; Jens Baumert; Andrea Schneider; Birgitt Marten-Mittag; Christa Meisinger; Natalia Erazo; Gaël P Hammer; Karl-Heinz Ladwig
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2010-09-21       Impact factor: 4.328

3.  Post-traumatic stress disorder in patients treated for schizophrenia: A cross-sectional study in the psychiatric department of Oujda, Morocco.

Authors:  Salah-Eddine El Jabiry; Mohamed Barrimi; Bouchra Oneib; Fatima El Ghazouani
Journal:  Ann Med Surg (Lond)       Date:  2022-04-25

4.  Suicide attempt and suicidal ideation and their associations with demographic and clinical correlates and quality of life in Chinese schizophrenia patients.

Authors:  Fang Yan; Yu-Tao Xiang; Ye-Zhi Hou; Gabor S Ungvari; Lisa B Dixon; Sandra S M Chan; Edwin H M Lee; Weng-Yong Li; Wen-Xiu Li; Yu-Ling Zhu; Helen F K Chiu
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2012-07-31       Impact factor: 4.328

5.  Mood instability, mental illness and suicidal ideas: results from a household survey.

Authors:  Steven Marwaha; Nick Parsons; Matthew Broome
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2013-01-24       Impact factor: 4.328

6.  Analysis of kinase gene expression in the frontal cortex of suicide victims: implications of fear and stress.

Authors:  Kwang Choi; Thien Le; Guoqiang Xing; Luke R Johnson; Robert J Ursano
Journal:  Front Behav Neurosci       Date:  2011-07-28       Impact factor: 3.558

7.  Suicide prevention in schizophrenia spectrum disorders and psychosis: a systematic review.

Authors:  Tara Donker; Alison Calear; Janie Busby Grant; Bregje van Spijker; Katherine Fenton; Kanupriya Kalia Hehir; Pim Cuijpers; Helen Christensen
Journal:  BMC Psychol       Date:  2013-04-30

8.  Discerning undifferentiated anxiety from syndromal anxiety in acute-phase schizophrenia.

Authors:  Kalai Naidu; Werdie van Staden; Lizelle Fletcher
Journal:  Ann Gen Psychiatry       Date:  2020-04-15       Impact factor: 3.455

9.  Validity and Reliability of the Staden Schizophrenia Anxiety Rating Scale.

Authors:  Werdie Van Staden; Antonia Dlagnekova; Kalai Naidu
Journal:  Diagnostics (Basel)       Date:  2022-03-28

Review 10.  Complex PTSD, affect dysregulation, and borderline personality disorder.

Authors:  Julian D Ford; Christine A Courtois
Journal:  Borderline Personal Disord Emot Dysregul       Date:  2014-07-09
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