Literature DB >> 20711209

mGluR2-Positive allosteric modulators: Therapeutic potential for treating cocaine abuse?

James E Barrett1.   

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Year:  2010        PMID： 20711209      PMCID： PMC3055298          DOI： 10.1038/npp.2010.93

Source DB:  PubMed          Journal:  Neuropsychopharmacology        ISSN： 0893-133X            Impact factor:   7.853


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  8 in total

1.  Discovery of allosteric potentiators for the metabotropic glutamate 2 receptor: synthesis and subtype selectivity of N-(4-(2-methoxyphenoxy)phenyl)-N-(2,2,2- trifluoroethylsulfonyl)pyrid-3-ylmethylamine.

Authors:  Michael P Johnson; Melvyn Baez; G Erik Jagdmann; Thomas C Britton; Thomas H Large; David O Callagaro; Joseph P Tizzano; James A Monn; Darryle D Schoepp
Journal:  J Med Chem       Date:  2003-07-17       Impact factor: 7.446

Review 2.  Discovery of drugs to treat cocaine dependence: behavioral and neurochemical effects of atypical dopamine transport inhibitors.

Authors:  Gianluigi Tanda; Amy H Newman; Jonathan L Katz
Journal:  Adv Pharmacol       Date:  2009-11-27

Review 3.  Glutamate-based therapeutic approaches: allosteric modulators of metabotropic glutamate receptors.

Authors:  Michael J Marino; P Jeffrey Conn
Journal:  Curr Opin Pharmacol       Date:  2005-12-20       Impact factor: 5.547

Review 4.  Metabotropic glutamate receptors as novel targets for anxiety and stress disorders.

Authors:  Chad J Swanson; Mark Bures; Michael P Johnson; Anni-Maija Linden; James A Monn; Darryle D Schoepp
Journal:  Nat Rev Drug Discov       Date:  2005-02       Impact factor: 84.694

5.  Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice.

Authors:  Ruggero Galici; Carrie K Jones; Kamondanai Hemstapat; Yi Nong; Nicholas G Echemendia; Lilly C Williams; Tomas de Paulis; P Jeffrey Conn
Journal:  J Pharmacol Exp Ther       Date:  2006-04-11       Impact factor: 4.030

6.  The mGluR2 positive allosteric modulator BINA decreases cocaine self-administration and cue-induced cocaine-seeking and counteracts cocaine-induced enhancement of brain reward function in rats.

Authors:  Xinchun Jin; Svetlana Semenova; Li Yang; Robert Ardecky; Douglas J Sheffler; Russell Dahl; P Jeffrey Conn; Nicholas D P Cosford; Athina Markou
Journal:  Neuropsychopharmacology       Date:  2010-06-16       Impact factor: 7.853

7.  Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial.

Authors:  Sandeep T Patil; Lu Zhang; Ferenc Martenyi; Stephen L Lowe; Kimberley A Jackson; Boris V Andreev; Alla S Avedisova; Leonid M Bardenstein; Issak Y Gurovich; Margarita A Morozova; Sergey N Mosolov; Nikolai G Neznanov; Alexander M Reznik; Anatoly B Smulevich; Vladimir A Tochilov; Bryan G Johnson; James A Monn; Darryle D Schoepp
Journal:  Nat Med       Date:  2007-09-02       Impact factor: 53.440

8.  Reinforcing effects of sigma-receptor agonists in rats trained to self-administer cocaine.

Authors:  Takato Hiranita; Paul L Soto; Gianluigi Tanda; Jonathan L Katz
Journal:  J Pharmacol Exp Ther       Date:  2009-11-05       Impact factor: 4.030
  8 in total
  1 in total

Review 1.  Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate Receptors.

Authors:  Craig W Lindsley; Kyle A Emmitte; Corey R Hopkins; Thomas M Bridges; Karen J Gregory; Colleen M Niswender; P Jeffrey Conn
Journal:  Chem Rev       Date:  2016-02-16       Impact factor: 60.622
  1 in total

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