Literature DB >> 20709555

Spinal epidural lipomatosis due to a bronchial ACTH-secreting carcinoid tumour.

K Bhatia1, E Frydenberg, T Steel, M Ow-Yang, K Ho, E Grainger.   

Abstract

Spinal epidural lipomatosis (SEL) is a rare condition characterized by abnormal deposits of fat in the epidural space. In a severe form this may cause compression of neural elements. This is the second report of SEL secondary to a carcinoid tumour. Our patient was a 34-year-old Caucasian male farm worker presenting with acute spinal cord compression. He had gained 11kg, and had developed Type II diabetes mellitus in the preceding 12months. On examination he displayed characteristic features of Cushing's syndrome. MRI demonstrated posterior epidural lipomatosis, with cord compression from T3 to T8. Urgent spinal cord decompression was performed. Further investigation confirmed a biochemical Cushing's syndrome secondary to an ACTH-producing pulmonary carcinoid tumour.
Copyright © 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 20709555     DOI: 10.1016/j.jocn.2010.04.008

Source DB:  PubMed          Journal:  J Clin Neurosci        ISSN: 0967-5868            Impact factor:   1.961


  6 in total

Review 1.  [Spinal epidural lipomatosis].

Authors:  J Artner; F Leucht; B Cakir; H Reichel; F Lattig
Journal:  Orthopade       Date:  2012-11       Impact factor: 1.087

Review 2.  Spinal Epidural Lipomatosis: A Comprehensive Review.

Authors:  Paul B Walker; Cain Sark; Gioe Brennan; Taylor Smith; William F Sherman; Alan D Kaye
Journal:  Orthop Rev (Pavia)       Date:  2021-07-11

3.  Spinal epidural lipomatosis: a rare and frequently unrecognized complication of Cushing syndrome.

Authors:  Noha Mukhtar; Ali S Alzahrani
Journal:  Endocrine       Date:  2022-03-08       Impact factor: 3.925

4.  An unusual case of spinal cord compression from concomitant spinal epidural lipomatosis and Hodgkin's lymphoma.

Authors:  Hasib Ahmadzai; Ali Khalil; Ruth A Mitchell; Bernard Kwok
Journal:  J Surg Case Rep       Date:  2016-03-08

Review 5.  Spinal Epidural Lipomatosis: A Review of Pathogenesis, Characteristics, Clinical Presentation, and Management.

Authors:  Keonhee Kim; Joseph Mendelis; Woojin Cho
Journal:  Global Spine J       Date:  2018-08-13

6.  Spinal epidural lipomatosis: a rare association of Cushing's disease.

Authors:  Sajjad Ahmad; Thomas Best; Andrew Lansdown; Caroline Hayhurst; Fiona Smeeton; Steve Davies; Aled Rees
Journal:  Endocrinol Diabetes Metab Case Rep       Date:  2020-10-19
  6 in total

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