Literature DB >> 20708943

Biodistribution of technetium-99m pertechnetate after total colectomy in rats.

Amália Cínthia Meneses Rêgo1, Rachel Alcântara Oliveira Ramalho, Eryvaldo Sócrates Tabosa Egito, Irami Araújo-Filho, Italo Medeiros Azevedo, Christopher J Palestro, Aldo Cunha Medeiros.   

Abstract

This study evaluated the effects of total colectomy on the biodistribution of technetium-99m pertechnetate ((99m)TcO(4)(-)) on the 28th postoperative day in rats. Samples of several organs were harvested for counting the percent of injected radioactivity/g of tissue (%ATI/g). The %ATI/g in colectomy rats was higher in the stomach and ileum than in sham and controls (p<0.05). Increase in mucosa and muscularis size of ileum was observed. Colectomy was associated with lower biodistribution in bladder and thyroid, T3, and T4, than in controls. Copyright 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 20708943     DOI: 10.1016/j.apradiso.2010.07.015

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN: 0969-8043            Impact factor:   1.513


  1 in total

1.  An experimental model to study the effects of a senna extract on the blood constituent labeling and biodistribution of a radiopharmaceutical in rats.

Authors:  Deise Elizabeth Souza; Marcia Oliveira Pereira; Luciana Camargo Bernardo; Fernanda Santos Carmo; Adenilson de Souza da Fonseca; Mario Bernardo-Filho
Journal:  Clinics (Sao Paulo)       Date:  2011       Impact factor: 2.365

  1 in total

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