João Aris Kouyoumdjian1, Erik V Stålberg2. 1. Faculdade de Medicina de São José do Rio Preto (FAMERP), Laboratório de Investigação Neuromuscular, São Paulo, Brazil. Electronic address: jaris@terra.com.br. 2. Department of Clinical Neurophysiology, Institute of Neurosciences, Uppsala University, Uppsala, Sweden.
Abstract
OBJECTIVES: The aim of this study was to estimate the jitter parameters in healthy controls in stimulated Orbicularis Oculi (OOc) muscle using concentric needle electrode (CNE). METHODS: Fifty healthy subjects, 13 males and 37 females (21-56 years, mean age of 38±9.2 years) were studied. The zygomatic branch of facial nerve was stimulated with a bar electrode. Jitter was expressed as the mean consecutive difference (MCD). Filter settings 1000 Hz-10 kHz. RESULTS: The mean MCD from individual studies (n=50, Gaussian distribution) was 21.5±1.99 μs (median=21 μs), ranging from 17.8 to 26 μs (upper limit, 97.5%, 25.5 μs). The mean and median MCD from all potentials (n=1500, non-Gaussian distribution) were 21.6 and 21 μs, ranging from 7.1 to 39 μs (upper limit, 97.5%, 33.4 μs). CONCLUSIONS: Suggested practical limits in the OOc for mean MCD was 26 μs and for outliers 34 μs. SIGNIFICANCE: Stimulation jitter recordings with CNE could be used in practice but borderline findings should be judged with great caution until larger database obtained with uniform setting available.
OBJECTIVES: The aim of this study was to estimate the jitter parameters in healthy controls in stimulated Orbicularis Oculi (OOc) muscle using concentric needle electrode (CNE). METHODS: Fifty healthy subjects, 13 males and 37 females (21-56 years, mean age of 38±9.2 years) were studied. The zygomatic branch of facial nerve was stimulated with a bar electrode. Jitter was expressed as the mean consecutive difference (MCD). Filter settings 1000 Hz-10 kHz. RESULTS: The mean MCD from individual studies (n=50, Gaussian distribution) was 21.5±1.99 μs (median=21 μs), ranging from 17.8 to 26 μs (upper limit, 97.5%, 25.5 μs). The mean and median MCD from all potentials (n=1500, non-Gaussian distribution) were 21.6 and 21 μs, ranging from 7.1 to 39 μs (upper limit, 97.5%, 33.4 μs). CONCLUSIONS: Suggested practical limits in the OOc for mean MCD was 26 μs and for outliers 34 μs. SIGNIFICANCE: Stimulation jitter recordings with CNE could be used in practice but borderline findings should be judged with great caution until larger database obtained with uniform setting available.
Authors: Chanika Alahakoon; Tharaka L Dassanayake; Indika B Gawarammana; E Michael Sedgwick; Vajira S Weerasinghe; Ahmed Abdalla; Michael S Roberts; Nicholas A Buckley Journal: PLoS One Date: 2018-09-27 Impact factor: 3.240