Literature DB >> 20707397

Biosynthesis of unnatural papaverine derivatives in Papaver somniferum.

E Brochmann-Hanssen1, C Y Chen, E E Linn.   

Abstract

The unnatural thebaine analog, oripavine 3-ethyl ether, was efficiently metabolized to morphine 3-ethyl ether and morphine in the opium poppy. An attempt to detect oripavine hy an isotope dilution experiment based on its presumed biosynthesis from reticuline was unsuccessful.

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Year:  1980        PMID： 20707397     DOI： 10.1021/np50012a007

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  2 in total

1.  The biosynthesis of papaverine proceeds via (S)-reticuline.

Authors:  Xu Han; Marc Lamshöft; Nadja Grobe; Xuan Ren; Anthony J Fist; Toni M Kutchan; Michael Spiteller; Meinhart H Zenk
Journal:  Phytochemistry       Date:  2010-05-20       Impact factor: 4.072

2.  Comparative transcriptome analysis using high papaverine mutant of Papaver somniferum reveals pathway and uncharacterized steps of papaverine biosynthesis.

Authors:  Sumya Pathak; Deepika Lakhwani; Parul Gupta; Brij Kishore Mishra; Sudhir Shukla; Mehar Hasan Asif; Prabodh Kumar Trivedi
Journal:  PLoS One       Date:  2013-05-30       Impact factor: 3.240
  2 in total

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