H Luo, H Quan, C Xie, Y Xu, L Fu, L Lou. Show Affiliations »
Abstract
Entities: Chemical
Mesh： See more » AminopyridinesAnimalsAntineoplastic Agents/pharmacologyApoptosis/drug effectsBenzamidesBlotting, WesternCell Proliferation/drug effectsDrug Resistance, Neoplasm/drug effectsFusion Proteins, bcr-abl/antagonists & inhibitorsFusion Proteins, bcr-abl/geneticsFusion Proteins, bcr-abl/metabolismHumansImatinib MesylateLeukemia, Experimental/drug therapyLeukemia, Experimental/metabolismLeukemia, Experimental/pathologyLeukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapyLeukemia, Myelogenous, Chronic, BCR-ABL Positive/metabolismLeukemia, Myelogenous, Chronic, BCR-ABL Positive/pathologyMiceMice, NudePhosphorylation/drug effectsPiperazines/pharmacologyProtein Kinase Inhibitors/pharmacologyProto-Oncogene Proteins c-kit/metabolismPyridines/pharmacologyPyrimidines/pharmacologyRNA, Messenger/geneticsReceptor, Platelet-Derived Growth Factor beta/metabolismReverse Transcriptase Polymerase Chain ReactionSurvival RateTumor Cells, CulturedXenograft Model Antitumor Assays
Substances： See more » AminopyridinesAntineoplastic AgentsBenzamidesPiperazinesProtein Kinase InhibitorsPyridinesPyrimidinesRNA, MessengerImatinib MesylateProto-Oncogene Proteins c-kitReceptor, Platelet-Derived Growth Factor betaFusion Proteins, bcr-ablflumatinib
Year: 2010 PMID： 20703259 DOI： 10.1038/leu.2010.169
Source DB: PubMed Journal: Leukemia ISSN： 0887-6924 Impact factor: 12.883