PURPOSE: To study the characteristics of patients with advanced open-angle glaucoma. METHODS: A hospital-based retrospective study was performed. Advanced glaucoma was defined as visual acuity of 0.3 or less, or mean deviation of -24 dB or less. First, we screened patients with advanced glaucoma and classified their glaucoma types. For patients with open-angle glaucoma (OAG), including both primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG), disc types were classified into four groups: focal ischemic (FI), myopic glaucomatous (MY), senile sclerotic (SS), and generalized cup enlargement (GE). RESULTS: After checking the medical history of 750 glaucoma patients, we classified 141 (18.8%) as having the advanced stage of the disease. The proportion of patients with advanced OAG was 47% (28% POAG, 19% NTG). The classification of optic disc appearances in OAG patients showed that in patients with POAG the predominant disc type was GE (P = 0.0012) and in those with NTG it was MY (P < 0.0001). CONCLUSION: In OAG patients in this study with severe glaucomatous damage, the predominant disc phenotype was GE in patients with POAG and MY in those with NTG.
PURPOSE: To study the characteristics of patients with advanced open-angle glaucoma. METHODS: A hospital-based retrospective study was performed. Advanced glaucoma was defined as visual acuity of 0.3 or less, or mean deviation of -24 dB or less. First, we screened patients with advanced glaucoma and classified their glaucoma types. For patients with open-angle glaucoma (OAG), including both primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG), disc types were classified into four groups: focal ischemic (FI), myopic glaucomatous (MY), senile sclerotic (SS), and generalized cup enlargement (GE). RESULTS: After checking the medical history of 750 glaucomapatients, we classified 141 (18.8%) as having the advanced stage of the disease. The proportion of patients with advanced OAG was 47% (28% POAG, 19% NTG). The classification of optic disc appearances in OAG patients showed that in patients with POAG the predominant disc type was GE (P = 0.0012) and in those with NTG it was MY (P < 0.0001). CONCLUSION: In OAG patients in this study with severe glaucomatous damage, the predominant disc phenotype was GE in patients with POAG and MY in those with NTG.
Authors: E Chihara; X Liu; J Dong; Y Takashima; M Akimoto; M Hangai; S Kuriyama; H Tanihara; M Hosoda; S Tsukahara Journal: Ophthalmologica Date: 1997 Impact factor: 3.250
Authors: Mae O Gordon; Julia A Beiser; James D Brandt; Dale K Heuer; Eve J Higginbotham; Chris A Johnson; John L Keltner; J Philip Miller; Richard K Parrish; M Roy Wilson; Michael A Kass Journal: Arch Ophthalmol Date: 2002-06
Authors: Ryan Caezar C David; Sasan Moghimi; Eren Ekici; Jiun L Do; Huiyuan Hou; James A Proudfoot; Alireza Kamalipour; Takashi Nishida; Christopher A Girkin; Jeffrey M Liebmann; Robert N Weinreb Journal: Am J Ophthalmol Date: 2021-04-25 Impact factor: 5.488
Authors: Yeji Moon; Junki Kwon; Da Woon Jeong; Jin Young Lee; Jong Rak Lee; Seungbong Han; Michael S Kook Journal: PLoS One Date: 2016-12-13 Impact factor: 3.240