Literature DB >> 20700705

What role does mitochondrial stress play in neurodegenerative diseases?

Alicia Mae Pickrell, Carlos Torres Moraes.   

Abstract

The essential need for mitochondrial function has been extensively shown to relate to neuronal health. Neurodegeneration and neurodegeneration-related diseases have been associated with multiple mitochondrial dysfunctions. This review highlights key findings related to commonly studied mitochondrial dysfunctions: imbalance of mitochondrial dynamics, mutations in the mitochondrial genome, excessive reactive oxygen species, and misfolded protein associations/interactions with the mitochondria. Future research in mitochondrial function will help elucidate complex neurodegenerative events while impacting both individual and societal health.

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Year:  2010        PMID： 20700705     DOI： 10.1007/978-1-60761-756-3_4

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  8 in total

Review 1.  Cell signaling and mitochondrial dynamics: Implications for neuronal function and neurodegenerative disease.

Authors:  Theodore J Wilson; Andrew M Slupe; Stefan Strack
Journal:  Neurobiol Dis       Date:  2012-01-24       Impact factor: 5.996

2.  The striatum is highly susceptible to mitochondrial oxidative phosphorylation dysfunctions.

Authors:  Alicia M Pickrell; Hirokazu Fukui; Xiao Wang; Milena Pinto; Carlos T Moraes
Journal:  J Neurosci       Date:  2011-07-06       Impact factor: 6.167

Review 3.  From expression QTLs to personalized transcriptomics.

Authors:  Stephen B Montgomery; Emmanouil T Dermitzakis
Journal:  Nat Rev Genet       Date:  2011-03-09       Impact factor: 53.242

4.  Early mitochondrial abnormalities in hippocampal neurons cultured from Fmr1 pre-mutation mouse model.

Authors:  Eitan S Kaplan; Zhengyu Cao; Susan Hulsizer; Flora Tassone; Robert F Berman; Paul J Hagerman; Isaac N Pessah
Journal:  J Neurochem       Date:  2012-09-28       Impact factor: 5.372

5.  A close look at axonal transport: Cargos slow down when crossing stationary organelles.

Authors:  Daphne L Che; Praveen D Chowdary; Bianxiao Cui
Journal:  Neurosci Lett       Date:  2015-10-31       Impact factor: 3.046

6.  Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells.

Authors:  Meryam Debbabi; Thomas Nury; Amira Zarrouk; Nadia Mekahli; Maryem Bezine; Randa Sghaier; Stéphane Grégoire; Lucy Martine; Philippe Durand; Emmanuelle Camus; Anne Vejux; Aymen Jabrane; Lionel Bretillon; Michel Prost; Thibault Moreau; Sofien Ben Ammou; Mohamed Hammami; Gérard Lizard
Journal:  Int J Mol Sci       Date:  2016-11-25       Impact factor: 5.923

7.  Protective Effects of Hydrolyzed Chicken Extract (Probeptigen®/Cmi-168) on Memory Retention and Brain Oxidative Stress in Senescence-Accelerated Mice.

Authors:  Ming-Yu Chou; Ying-Ju Chen; Liang-Hung Lin; Yoshihiro Nakao; Ai Lin Lim; Ming-Fu Wang; Shan May Yong
Journal:  Nutrients       Date:  2019-08-12       Impact factor: 5.717

8.  ROS production is essential for the apoptotic function of E2F1 in pheochromocytoma and neuroblastoma cell lines.

Authors:  Lilia Espada; Nathalie Meo-Evoli; Patricia Sancho; Sebastian Real; Isabel Fabregat; Santiago Ambrosio; Albert Tauler
Journal:  PLoS One       Date:  2012-12-12       Impact factor: 3.240
  8 in total

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