| Literature DB >> 20699556 |
Ki Yong Lee1, Lim Hwang, Eun Ju Jeong, Seung Hyun Kim, Young Choong Kim, Sang Hyun Sung.
Abstract
A methanolic extract of Agrimonia eupatoria (Rosaceae) significantly attenuated glutamate-induced oxidative stress in HT22 hippocampal cells. A new flavonoid, characterized as kaempferol 3-O-beta-D-(2''-O-acetyl-6''-(E)-p-coumaroyl)-glucopyranoside (2''-acetyl-tiliroside (1), was isolated from the methanolic extract of A. eupatoria stems together with nine known flavonoids. Compounds 4, 7, 8 and 9 all showed a neuroprotective effect on glutamate-induced toxicity in HT22 cells.Entities:
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Year: 2010 PMID: 20699556 DOI: 10.1271/bbb.100200
Source DB: PubMed Journal: Biosci Biotechnol Biochem ISSN: 0916-8451 Impact factor: 2.043