Literature DB >> 20699555

Kaempferol enhanced the intracellular thioredoxin system in normal cultured human keratinocytes.

Misato Sugahara1, Jotaro Nakanishi, Yuji Katsuta.   

Abstract

The effects of kaempferol on redox-associated enzymes in normal human keratinocytes were studied. It enhanced the gene expression of thioredoxin reductase 1 and thioredoxin. Flavonols had higher ability to induce the expression of these genes than the other anti-oxidants and the other flavonoids tested. Furthermore, kaempferol and quercetin increased the activity of thioredoxin reductase in normal human keratinocytes.

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Year:  2010        PMID: 20699555     DOI: 10.1271/bbb.100166

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN: 0916-8451            Impact factor:   2.043


  2 in total

1.  Induction of Thioredoxin Reductase 1 by Korean Red Ginseng Water Extract Regulates Cytoprotective Effects on Human Endothelial Cells.

Authors:  Hye Rim Park; Seung Eun Lee; Hana Yang; Gun Woo Son; Young-Ho Jin; Yong Seek Park
Journal:  Evid Based Complement Alternat Med       Date:  2015-07-08       Impact factor: 2.629

2.  Effect of Kaempferol and Its Glycoside Derivatives on Antioxidant Status of HL-60 Cells Treated with Etoposide.

Authors:  Magdalena Kluska; Michał Juszczak; Jerzy Żuchowski; Anna Stochmal; Katarzyna Woźniak
Journal:  Molecules       Date:  2022-01-06       Impact factor: 4.411

  2 in total

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