BACKGROUND: Transverse myelitis has been reported in association with vaccination, including influenza vaccination. OBJECTIVE: To describe a case of longitudinally extensive transverse myelitis associated with vaccination with a nasal attenuated novel influenza A(H1N1) vaccine. DESIGN: Case report. SETTING: Sanford University of South Dakota Hospital. Patient A 27-year-old woman with longitudinally extensive transverse myelitis. RESULTS: Four days following novel influenza A(H1N1) vaccination, the patient developed longitudinally extensive transverse myelitis. Extensive diagnostic evaluation effectively ruled out causes other than vaccination-associated transverse myelitis. Following treatment with corticosteroids and plasmapheresis, the patient made a significant recovery. CONCLUSIONS: Transverse myelitis may be associated with vaccination against novel influenza A(H1N1). Additionally, we believe this to be the first report of longitudinally extensive transverse myelitis associated with any vaccine.
BACKGROUND:Transverse myelitis has been reported in association with vaccination, including influenza vaccination. OBJECTIVE: To describe a case of longitudinally extensive transverse myelitis associated with vaccination with a nasal attenuated novel influenza A(H1N1) vaccine. DESIGN: Case report. SETTING: Sanford University of South Dakota Hospital. Patient A 27-year-old woman with longitudinally extensive transverse myelitis. RESULTS: Four days following novel influenza A(H1N1) vaccination, the patient developed longitudinally extensive transverse myelitis. Extensive diagnostic evaluation effectively ruled out causes other than vaccination-associated transverse myelitis. Following treatment with corticosteroids and plasmapheresis, the patient made a significant recovery. CONCLUSIONS:Transverse myelitis may be associated with vaccination against novel influenza A(H1N1). Additionally, we believe this to be the first report of longitudinally extensive transverse myelitis associated with any vaccine.
Authors: Asha Prerna; Jocelyn Y X Lim; Natalie W H Tan; Mas Suhaila Isa; Helen May-Lin Oh; Norazieda Yassin; Chian-Yong Low; Derrick W S Chan; Chia-Yin Chong; Yee-Sin Leo; Angela Li-Ping Chow; Paul Ananth Tambyah; Kevin Tan Journal: J Neurovirol Date: 2015-04-28 Impact factor: 2.643
Authors: Gustavo C Román; Fernando Gracia; Antonio Torres; Alexis Palacios; Karla Gracia; Diógenes Harris Journal: Front Immunol Date: 2021-04-26 Impact factor: 7.561