Literature DB >> 20696726

Intranasal medication delivery for children: a brief review and update.

Timothy R Wolfe1, Darren A Braude.   

Abstract

With the exception of oral medications, most traditional forms of drug delivery outside the operating suite require an injection with a needle-a process that is painful and anxiety-provoking, risks needle stick injury, and consumes valuable staff time. In addition, intravenous access in pediatrics may be difficult for inexperienced providers. Intranasal medication delivery offers an alternative method of drug delivery that is often as fast in onset as intravenous medication, usually painless, inexpensive, easy to deliver, and effective in a variety of acute pediatric medical conditions. This article briefly reviews the most common uses for intranasal medication delivery in pediatrics: pain control, anxiolysis, and seizure control.

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Year:  2010        PMID: 20696726     DOI: 10.1542/peds.2010-0616

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  35 in total

1.  Expanding access to naloxone in the United States.

Authors:  Suzanne Doyon; Steven E Aks; Scott Schaeffer
Journal:  J Med Toxicol       Date:  2014-12

Review 2.  [Burns and scalds in children].

Authors:  B Landsleitner; J Keil
Journal:  Med Klin Intensivmed Notfmed       Date:  2015-06       Impact factor: 0.840

Review 3.  Intranasal therapy with opioids for children and adolescents with cancer: results from clinical studies.

Authors:  Silvia Triarico; Michele Antonio Capozza; Stefano Mastrangelo; Giorgio Attinà; Palma Maurizi; Antonio Ruggiero
Journal:  Support Care Cancer       Date:  2019-06-01       Impact factor: 3.603

4.  An open-label randomised controlled trial on the efficacy of adding intranasal fentanyl to intravenous tramadol in patients with moderate to severe pain following acute musculoskeletal injuries.

Authors:  Keng Sheng Chew; Abdul Hafiz Shaharudin
Journal:  Singapore Med J       Date:  2016-05-19       Impact factor: 1.858

5.  Optimal Volume of Administration of Intranasal Midazolam in Children: A Randomized Clinical Trial.

Authors:  Daniel S Tsze; Maria Ieni; Daniel B Fenster; John Babineau; Joshua Kriger; Bruce Levin; Peter S Dayan
Journal:  Ann Emerg Med       Date:  2016-11-04       Impact factor: 5.721

Review 6.  Intranasal Dexmedetomidine for Procedural Sedation in Children, a Suitable Alternative to Chloral Hydrate.

Authors:  Giorgio Cozzi; Stefania Norbedo; Egidio Barbi
Journal:  Paediatr Drugs       Date:  2017-04       Impact factor: 3.022

7.  Recombinant Slit2 attenuates neuronal apoptosis via the Robo1-srGAP1 pathway in a rat model of neonatal HIE.

Authors:  Harpreet Kaur; Ningbo Xu; Desislava Met Doycheva; Jay Malaguit; Jiping Tang; John H Zhang
Journal:  Neuropharmacology       Date:  2019-07-26       Impact factor: 5.250

8.  A randomized clinical trial comparing oral, aerosolized intranasal, and aerosolized buccal midazolam.

Authors:  Eileen J Klein; Julie C Brown; Ana Kobayashi; Daniel Osincup; Kristy Seidel
Journal:  Ann Emerg Med       Date:  2011-10       Impact factor: 5.721

9.  Comparison of the effects of intranasal midazolam versus different doses of intranasal ketamine on reducing preoperative pediatric anxiety: a prospective randomized clinical trial.

Authors:  S A Hosseini Jahromi; S M Hosseini Valami; Nematollah Adeli; Zohreh Yazdi
Journal:  J Anesth       Date:  2012-06-12       Impact factor: 2.078

Review 10.  [Pediatric emergencies in the emergency medical service].

Authors:  C Silbereisen; F Hoffmann
Journal:  Anaesthesist       Date:  2015-01       Impact factor: 1.041

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