[The transcription factor NF-kappaB in human diseases].

The transcription nuclear factor kappa B (NF-kappaB) was first described in 1986. Currently, the NF-kappaB has been linked to several metabolic and inflammatory diseases as well as to several types of cancer. NF-kappaB will continue to be of interest in many disease processes such as inflammatory, infectious and neoplastic. The discovery of this factor has increased our knowledge about the regulation of inflammation and chronic diseases, as well as the medications used to treat those diseases.